Reactivity | HuSpecies Glossary |
Applications | ELISA, ICC/IF, IHC, IP |
Clone | Ali 12-28 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Format | BSA Free |
Concentration | 1 mg/ml |
Immunogen | N-terminal APC-MBP fusion protein |
Localization | Cytoplasmic and Nuclear |
Specificity | Ali 12-28 detects both normal and mutant-truncated forms of the APC. |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | APC |
Purity | Protein A purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | This antibody has been used routinely for Western blotting on colon cell line HCT116, SW480 and SW837 extracts. Use in Immunohistochemistry-paraffin reported in scientific literature (Awadalla A et al). |
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Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer | PBS |
Preservative | 0.02% Sodium Azide |
Concentration | 1 mg/ml |
Purity | Protein A purified |
Publications using NB100-667 | Applications | Species |
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Awadalla A, Aboelenin H, Hemmaid KZ. Pattern of DNA Hypermethylation of APC, P16, P73, P16, O 6 MMGT, CD99 and CDH1 Genes in Bladder Cancer with Hepatitis C Viral (HCV) Infection International Journal of Cancer Research 2015-08-06 (IHC-P, Human) | IHC-P | Human |
Ranes M, Zaleska M, Sakalas S Et al. Reconstitution of the destruction complex defines roles of AXIN polymers and APC in beta-catenin capture, phosphorylation, and ubiquitylation Molecular cell 2021-08-19 [PMID: 34352208] (WB, Human) | WB | Human |
Abutaily AS et al. Cadherins, catenins APC in pleural malignant mesothelioma. J Pathol 201:355-62. 2003-01-01 [PMID: 14595746] |
Secondary Antibodies |
Isotype Controls |
Research Areas for APC Antibody (NB100-667)Find related products by research area.
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The role of MHC Class II RT1B and immune response post brain injury The major histocompatibility complex (MHC) is responsible for binding peptide fragments arising from pathogens in order to display them on the cell surface for recognition from immune cells. Once recognized, the foreign pathogen is typically evade... Read full blog post. |
Beta-catenin - I am versatile! Beta-catenin is a cytosolic, 88 kDa intracellular protein associated with cell surface cadherin glycoproteins. It is a member of the larger calcium-dependent catenin family that includes alpha-catenin, beta-catenin, and gamma-catenin (also known as pl... Read full blog post. |
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