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Aminopeptidase LRAP/ERAP2 Antibody [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

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Aminopeptidase LRAP/ERAP2 Antibody [FITC] Summary

Immunogen
ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 . Amino Acid Squence: LQSEEDSRYMKPGKELK
Specificity
Aminopeptidase LRAP/ERAP2 antibody is human reactive. Multiple isoforms of Aminopeptidase LRAP/ERAP2 are known to exist. Aminopeptidase LRAP/ERAP2 antibody is predicted to not cross-react with ERAP1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERAP2
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for Aminopeptidase LRAP/ERAP2 Antibody [FITC]

  • Aminopeptidase LRAP
  • EC 3.4.11
  • EC 3.4.11.3
  • endoplasmic reticulum aminopeptidase 2
  • ERAP2
  • FLJ23633
  • FLJ23701
  • FLJ23807
  • Leukocyte-derived arginine aminopeptidase
  • LRAPL-RAPEC 3.4.11.-

Background

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 190470) (Tanioka et al., 2003 [PubMed 12799365]).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ERAP2