Home » Aminopeptidase LRAP/ERAP2 » ERAP2 Antibodies » Aminopeptidase LRAP/ERAP2 Antibody
Novus Biologicals products are now on bio-techne.com

Aminopeptidase LRAP/ERAP2 Antibody

 (12 Publications)
 (1 Review)
 See All Related
Submit a Review

Images

 
(
Enlarge)
Immunoblot analyses of ERAP2 using LCL protein extract.Two LCLs of each ERAP2 genotype (AA, AB, and BB) were tested for protein using primary antibodies specific to: A, ERAP2 (goat polyclonal); B, ERAP2 (mouse polyclonal); and C, beta -actin (see Materials and Methods). Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pgen.1001157), licensed under a CC-BY license. Not internally tested by R&D Systems.
Immunoblot analyses of ERAP2 using LCL protein extract.Two LCLs of each ERAP2 genotype (AA, AB, and BB) were tested for protein using primary antibodies specific to: A, ERAP2 (goat polyclonal); B, ERAP2 (mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Biotin
BAF3830
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF3830-SP
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Aminopeptidase LRAP/ERAP2 Antibody Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Aminopeptidase LRAP/ERAP2
Ala56-Thr960
Accession # Q6P179
Specificity
Detects human Aminopeptidase LRAP/ERAP2 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ERAP2
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunoprecipitation 25 ug/mL
  • Western Blot 0.1 ug/mL
Reviewed Applications
Read 1 Review rated 4
using
AF3830 in the following applications:
Publications
Read Publications using
AF3830 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Aminopeptidase LRAP/ERAP2 Antibody

  • Aminopeptidase LRAP
  • EC 3.4.11
  • EC 3.4.11.3
  • endoplasmic reticulum aminopeptidase 2
  • ERAP2
  • FLJ23633
  • FLJ23701
  • FLJ23807
  • Leukocyte-derived arginine aminopeptidase
  • LRAPL-RAPEC 3.4.11.-

Background

Leukocyte-derived arginine aminopeptidase (LRAP) and endoplasmic reticulum-aminopeptidase 2 (ERAP2) are the two names given to the protein encoded by the LRAP gene (1, 2). Induced by interferon-gamma , LRAP is able to trim various MHC class I antigenic peptide precursors. It belongs to the oxytocinase subfamily of M1 aminopeptidases, which also includes aminopeptidases PILS/ARTS1/ERAP1 and LNPEP/PLAP (1, 3). In addition to antigen presentation, the members of this subfamily are also important in maintenance of pregnancy, memory retention, and blood pressure regulation (3).

  1. Tanioka, T. et al. (2003) J. Biol. Chem. 278:32275.
  2. Tanioka, T. et al. (2005) FEBS J. 272:916.
  3. Tsujimoto, M. and A. Hattori (2005) Biochim. Biophys. Acta 1751:9.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Aminopeptidase
PILS/ARTS1 Antibody [ ...
AF2334
Western Blot Aminopeptidase PILS/ARTS1 Antibody [Unconjugated]
Immunocytochemistry Aminopeptidase PILS/ARTS1 Antibody [Unconjugated]
Immunohistochemistry Aminopeptidase PILS/ARTS1 Antibody [Unconjugated]
(11 Publications)
Species: Hu
Applications: ICC, IHC, IP, Simple Western, WB
Leucyl-cystinyl
Aminopeptidase/LNPEP ...
AF6386
Western Blot Leucyl-cystinyl Aminopeptidase/LNPEP Antibody
Species: Hu
Applications: IP, WB
AMELX Antibody
NBP2-15373
Western Blot AMELX Antibody
Western Blot AMELX Antibody
Species: Hu, Mu
Applications: WB
TRACP/PAP/ACP5
Antibody
H00000054-D01P
Western Blot TRACP/PAP/ACP5 Antibody
Western Blot TRACP/PAP/ACP5 Antibody
(3 Publications)
Species: Hu, Mu
Applications: IHC, IHC-P, WB
TDRD7 Antibody
NBP1-87315
Immunohistochemistry TDRD7 Antibody
(1 Publication)
Species: Hu
Applications: IHC, IHC-P
CD40 Ligand/TNFSF5
[HRP]
DCDL40
N/A CD40 Ligand/TNFSF5 [HRP]
N/A CD40 Ligand/TNFSF5 [HRP]
(44 Publications)
Species: Hu
Applications: ELISA
SCYL1 Antibody
(2E5)
H00057410-M02
Sandwich ELISA SCYL1 Antibody (2E5)
Western Blot SCYL1 Antibody (2E5)
Western Blot SCYL1 Antibody (2E5)
(1 Publication)
Species: Hu, Mu, Rt
Applications: ELISA, S-ELISA, WB
TRAF-2 Antibody
NB100-56173
Immunocytochemistry/ Immunofluorescence TRAF-2 Antibody
Immunohistochemistry TRAF-2 Antibody
Immunohistochemistry-Paraffin TRAF-2 Antibody
(4 Publications)
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, IP, WB
LAMP-1/CD107a
Antibody
NB120-19294
Western Blot LAMP-1/CD107a Antibody
Immunocytochemistry/ Immunofluorescence LAMP-1/CD107a Antibody
Immunocytochemistry/ Immunofluorescence LAMP-1/CD107a Antibody
(2 Reviews)
(36 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Osteopontin/OPN
Antibody [Unconjugate
AF808
Immunocytochemistry Osteopontin/OPN Antibody [Unconjugated]
Neutralization Osteopontin/OPN Antibody [Unconjugated]
Immunohistochemistry Osteopontin/OPN Antibody [Unconjugated]
(2 Reviews)
(203 Publications)
Species: Mu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, IHC, Neut, WB
RANK/TNFRSF11A
Antibody (9A725) - BS ...
NB100-56508
Flow Cytometry RANK/TNFRSF11A Antibody (9A725) - BSA Free
Flow Cytometry RANK/TNFRSF11A Antibody (9A725) - BSA Free
Flow Cytometry RANK/TNFRSF11A Antibody (9A725) - BSA Free
(19 Publications)
Species: Av, Hu, Mu, Rt
Applications: CyTOF-ready, Flow-CS, Flow, IHC, IHC-P, WB

TRANCE/TNFSF11/RANK L
462-TR
SDS-PAGE TRANCE/TNFSF11/RANK L [Unconjugated]
Bioactivity TRANCE/TNFSF11/RANK L [Unconjugated]
(88 Publications)
Species: Mu
Applications: BA
sFRP-1
[Unconjugated]
5396-SF
sFRP-1 [Unconjugated]
(15 Publications)
Species: Hu
Applications: BA
CD8 Antibody
(53-6.7) - BSA Free
NBP1-49045
Immunohistochemistry-Paraffin CD8 Antibody (53-6.7) - BSA Free
Immunocytochemistry/ Immunofluorescence CD8 Antibody (53-6.7) - BSA Free
Immunohistochemistry-Frozen CD8 Antibody (53-6.7) - BSA Free
(3 Reviews)
(28 Publications)
Species: Mu, Rt
Applications: Cell Depl, CyTOF-ready, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, InhibTFunc
Aminopeptidase
B/RNPEP Antibody
NBP2-54975
Western Blot Aminopeptidase B/RNPEP Antibody
Immunocytochemistry/ Immunofluorescence Aminopeptidase B/RNPEP Antibody
Immunohistochemistry-Paraffin Aminopeptidase B/RNPEP Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Muscarinic
Acetylcholine Recepto ...
NBP1-87466
Immunohistochemistry-Paraffin Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody
Immunohistochemistry-Paraffin Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody
Immunocytochemistry/ Immunofluorescence Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody
(1 Review)
(5 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC-FrFl, IHC, IHC-Fr, IHC-P, WB
Osteocalcin
Antibody (190125)
MAB1419
Intracellular Staining by Flow Cytometry Osteocalcin Antibody (190125)
Intracellular Staining by Flow Cytometry Osteocalcin Antibody (190125)
Immunocytochemistry Osteocalcin Antibody (190125)
(3 Reviews)
(54 Publications)
Species: Hu, Rt
Applications: CyTOF-ready, ICC, IHC, ICFlow
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(808 Publications)
Species: Hu
Applications: BA

Osteoprotegerin/TNFRSF
DY805
N/A Osteoprotegerin/TNFRSF11B [Biotin]
(89 Publications)
Species: Hu
Applications: ELISA
Aminopeptidase
LRAP/ERAP2 Antibody
AF3830
Aminopeptidase LRAP/ERAP2 Antibody
Species: Hu
Applications: WB, IP

Publications for Aminopeptidase LRAP/ERAP2 Antibody (AF3830)(12)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 4 applications: ICC, IHC, IHC-P, Western Blot.


Filter By Application
ICC
(1)
IHC
(2)
IHC-P
(1)
Western Blot
(4)
All Applications
Filter By Species
Human
(4)
All Species
Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using AF3830 Applications Species
I Temponeras, G Stamatakis, M Samiotaki, D Georgiadis, H Pratsinis, G Panayotou, E Stratikos ERAP2 Inhibition Induces Cell-Surface Presentation by MOLT-4 Leukemia Cancer Cells of Many Novel and Potentially Antigenic Peptides International Journal of Molecular Sciences, 2022-02-08;23(3):. 2022-02-08 [PMID: 35163832] (Western Blot, Human) Western Blot Human
Wouter J. Venema, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander et al. ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29 Frontiers in Immunology 2/25/2021 [PMID: 33717175]
P Jiang, RN Veenstra, A Seitz, IM Nolte, BG Hepkema, L Visser, A van den Be, A Diepstra Interaction between ERAP Alleles and HLA Class I Types Support a Role of Antigen Presentation in Hodgkin Lymphoma Development Cancers, 2021-01-22;13(3):. 2021-01-22 [PMID: 33499248] (IHC, Western Blot, Human) IHC, Western Blot Human
Irma Saulle, Claudia Vanetti, Sara Goglia, Chiara Vicentini, Enrico Tombetti, Micaela Garziano et al. A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection? Cells 8/24/2020 [PMID: 32847031]
Kimberly Seamon, Lesia O. Kurlak, Michelle Warthan, Efstratios Stratikos, Jerome F. Strauss, Hiten D. Mistry et al. The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia Frontiers in Immunology 3/10/2020 [PMID: 32210971]
Despoina Koumantou, Eilon Barnea, Adrian Martin-Esteban, Zachary Maben, Athanasios Papakyriakou, Anastasia Mpakali et al. Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1) Cancer Immunology, Immunotherapy 8/1/2019 [PMID: 31222486]
Chun Jimmie Ye, Jenny Chen, Alexandra-Chloé Villani, Rachel E. Gate, Meena Subramaniam, Tushar Bhangale et al. Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection Genome Research 12/1/2018 [PMID: 30446528]
Jonas J W Kuiper, Jessica van van Setten, Matthew Devall, Mircea Cretu-Stancu, Sanne Hiddingh, Roel A Ophoff et al. Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis Human Molecular Genetics 9/28/2018 [PMID: 30215709]
CC Wu, JD Lin, JT Chen, CM Chang, HF Weng, C Hsueh, HP Chien, JS Yu Integrated analysis of fine-needle-aspiration cystic fluid proteome, cancer cell secretome, and public transcriptome datasets for papillary thyroid cancer biomarker discovery Oncotarget, 2018-01-04;9(15):12079-12100. 2018-01-04 [PMID: 29552294] (IHC, Western Blot, Human) IHC, Western Blot Human
MD Warthan, SL Washington, SE Franzese, RM Ramus, KR Kim, TP York, E Stratikos, JF Strauss, ED Lee The role of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) in modulating immune detection of choriocarcinoma Biol. Reprod., 2018-03-01;0(0):. 2018-03-01 [PMID: 29324974] (ICC, IHC-P, Western Blot, Human) ICC, IHC-P, Western Blot Human
Show All 12 Publications.

Review for Aminopeptidase LRAP/ERAP2 Antibody (AF3830) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using AF3830:
Filter by Applications
WB
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
  4
reviewed by:
Verified Customer
 WB Human 01/08/2015
View

Summary

ApplicationWestern Blot
Sample TestedSee PMID 24040622
SpeciesHuman

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Aminopeptidase LRAP/ERAP2 Antibody (AF3830) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Aminopeptidase LRAP/ERAP2 Products

Blogs on Aminopeptidase LRAP/ERAP2

There are no specific blogs for Aminopeptidase LRAP/ERAP2, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Recent Reviews

4
5
0
4
1
3
0
2
0
1
0
 
 Verified Customer
01/08/2015
Application: WB
Species: Human
read this review

Bioinformatics

Gene Symbol ERAP2
Uniprot