Adenosine A2b R Antibody - BSA Free

The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: FLOW, IF/IHC, WB.

Showing Publications 1 - 7 of 7.

Publications using NBP2-41312	Applications	Species
Bao Q, Ganbold T, Qiburi Q et al. AMP functionalized curdlan nanoparticles as a siRNA carrier: Synthesis, characterization and targeted delivery via adenosine A(2B) receptor Int J Biol Macromol 2021-12-01 [PMID: 34743942] (Human)		Human
Pang L, Ng KT, Liu J et al. Plasmacytoid dendritic cells recruited by HIF-1 alpha /eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma Cancer letters 2021-09-16 [PMID: 34536555] (FLOW, Human)	FLOW	Human
Basu, M, Gupta, P Et al. Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing Leishmania infection. J Cell Sci 2020-04-08 [PMID: 32079656] (IF/IHC, Mouse)	IF/IHC	Mouse
Witteveldt J, Knol LI, Macias S Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema Dis Model Mech 2019-05-15 [PMID: 31036697] (WB)	WB
Lan J, Lu H, Samanta D et al. Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment. Proc Natl Acad Sci U S A. 2018-10-09 [PMID: 30242135] (FLOW, Human) Details: Citation using the PE form of this antibody.	FLOW	Human
Xu X, Zhu Q, Niu F et al. A2BAR activation attenuates acute lung injury by inhibiting alveolar epithelial cell apoptosis both in vivo and in vitro Am. J. Physiol., Cell Physiol. 2018-06-13 [PMID: 29898376] (Mouse)		Mouse
Ren ZH, Lin CZ, Cao W et al. CD73 is associated with poor prognosis in HNSCC. Oncotarget. 2016-09-20 [PMID: 27557512] (IF/IHC, WB, Human)	IF/IHC, WB	Human

Array NBP2-41312

• Adenosine A2b R Antibodies
• Adenosine A2b R ELISA Kits
• Adenosine A2b R Lysate