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Adenosine A2b R Antibody [DyLight 680]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 680

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Adenosine A2b R Antibody [DyLight 680] Summary

Immunogen
Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ADORA2B. The immunogen is located within the last 50 amino acids of ADORA2B. Amino Acid Squence: QADVKSGNGQAGVQPA
Specificity
At least two isoforms of ADORA2B are known to exist; this antibody will detect both isoforms. ADORA2B antibody is predicted to not cross-react with ADORA2A.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADORA2B
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rabbit (80%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Adenosine A2b R Antibody [DyLight 680]

  • Adenosine A2b R
  • adenosine A2b receptor
  • Adenosine A2bR
  • adenosine receptor A2b
  • ADORA2
  • ADORA2B

Background

The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADORA2B