ACF1 Antibody

ACF1/BAZ1A is a subunit of the ACF chromatin-remodeling complex and the ISWI CHRAC remodeling complex. In the ACF complex, ACF1/BAZ1A functions to influence the nucleosome remodeling activity of the SNF2h ATPase. As part of the CHRAC complex, ACF1/BAZ1A may function to target CHRAC to heterochromatin. ACF1 has also been shown to interact with the nuclear receptor corepressor protein (N-CoR) to facilitate the repression of transcription by unliganded nuclear receptors. Alternate names for ACF1/BAZ1A include ATP-utilizing chromatin assembly and remodeling factor1, hACF1, bromodomain adjacent to zinc finger domain protein 1A, Williams syndrome transcription factor-related chromatin-remodeling factor 180, WCRF180, hWALp1, and CHRAC subunit ACF1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ICC/IF, IP, WB.

Showing Publications 1 - 4 of 4.

Publications using NB100-61041	Applications	Species
Koyauchi T, Niida H, Motegi A et al. Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair Biochimica et biophysica acta. Molecular cell research 2022-11-01 [PMID: 35940372] (WB, Human)	WB	Human
Oppikofer M, Sagolla M, et al. Non-canonical reader modules of BAZ1A promote recovery from DNA damage. Nat Commun 2017-10-11 [PMID: 29021563] (ICC/IF, Human)	ICC/IF	Human
Aydin OZ, Marteijn JA, Ribeiro-Silva C et al. Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription. Nucleic Acids Res. 2014-09-01 [PMID: 24990377] (IP, WB, Human)	IP, WB	Human
Sanchez-Molina S, Mortusewicz O, Bieber B et al. Role for hACF1 in the G2/M damage checkpoint. Nucleic Acids Res 2011-10-01 [PMID: 21745822]

Array NB100-61041

• ACF1 Antibodies
• ACF1 Proteins