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OCT4

Breast cancer stem cells survive chemotherapy through S100A10-ANXA2-SPT6 interaction that epigenetically promotes OCT4-mediated stemness

Deriving neural precursor cells from human induced pluripotent stem cells

Application Focus: New Methods for iPSC Differentiation, Inducing a Mammary Fate

Stemness for Surviving Hypoxia: TGF-beta/Smad Signaling in Multiple Myeloma

Nanog is a Master Controller of ES cell Pluripotency

Nanog, a homeodomain (HD) transcription factor, plays a critical role in the maintenance of embryonic stem (ES) cell self-renewal. Transcription regulator involved in inner cell mass and ES cell proliferation and self-renewal.

Histones, Bmi1 & OCT4: Investigating the Secrets of ESC Pluripotency

Epigenetic alterations have come to prominence in biomedical research. In particular, hypermethylation of CpG islands located in the promoter regions of tumor-suppressor genes is now firmly established as an important mechanism for gene inactivation in cancer.

Sox2 and Oct4: Roles in Embryonic Stem Cell Pluripotency

Embryonic stem (ES) cells are cells derived from the inner cell mass of the blastocyst, an early-stage embryo. ES cells are distinguished from other cells due to their pluripotency, which is the ability to differentiate into any different type of cell in the body, and also their capability of propagating indefinitely. These two factors make embryonic stem cells valuable tools in the scientific community, especially in regenerative medicine.

An Unlikely Pairing: The SOX2 Antibody and Breast Cancer

SOX2 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, which play a vital role in embryonic development. SOX2 antibody research has identified Sox2 as a key transcription factor in pluripotent stem cells. We at Novus Biologicals offer a number of top quality SOX2 products in our stem cell antibody catalog.

The Sox2 Antibody Aids Brain Cancer Research

The Sox2 antibody is widely used in sensory, neuroscience and stem cell marker research. Recently, Sox2 antibody preparations identified the Sox2 protein as a marker for malignant neural gliomas. We at Novus Biologicals offer a wide variety of highly validated Sox2 antibodies.

Not as Pluripotent as You Used to Be: Embryonic Stem Cell Markers and the Aging Process

We at Novus Biologicals recently extended our antibody catalog to include several embryonic stem cells (ESC) antibodies validated for use in FACS (fluorescent activated cell sorting) assays. Among them was Oct4, which recently became the focus of an interesting study into the human aging process.

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