Recombinant Human YB1 His Protein

YBX1, also known as Y box binding protein 1, associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation. This protein is a potential drug target in cancer therapy. It helps the replication of adenovirus type 5, a commonly used vector in gene therapy. Thus, YBX1 can cause an "oncolytic" effect in YBX1 positive cancer cells treated with adenoviruses. Recombinant human YBX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: KA.

Showing Publications 1 - 4 of 4.

Publications using NBP2-30101	Applications	Species
Li Y, Guo Q, Xiao W, Xiao Y RNA-binding protein YBX1 promotes Type H vessels dependent bone formation in an m5C-dependent manner bioRxiv 2023-04-21
Li, YJ;Guo, Q;Ye, MS;Cai, G;Xiao, WF;Deng, S;Xiao, Y; YBX1 promotes type H vessel-dependent bone formation in an m5C-dependent manner JCI insight 2024-01-11 [PMID: 38385749]
McKernan CM, Khatri A, Hannigan M et al. ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain Cell reports 2022-08-30 [PMID: 36044842] (KA)	KA
Ogburn RN, Jin L, Meng H, Fitzgerald MC. Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements J. Proteome Res. 2017-09-19 [PMID: 28927269] (Human)		Human

Array NBP2-30101

• YB1 Antibodies
• YB1 ELISA Kits
• YB1 Lysate
• YB1 Proteins