Wnt-5a Antibody - BSA Free

Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: IF/IHC, IHC-P, WB.

Showing Publications 1 - 10 of 16. Show All 16 Publications. Collapse Publications.

Publications using NBP2-24752	Applications	Species
Illendula A, Fultang N, Peethambaran B Retinoic acid induces differentiation in neuroblastoma via ROR1 by modulating retinoic acid response elements Oncol. Rep. 2020-09-01 [PMID: 32705280] (WB, Human)	WB	Human
Zhang H, Yang X, Hu F et al. Expression Level of Wnt5a Was Related to the Therapeutic Effects of First-Generation EGFR-TKIs OTT 2020-06-01 [PMID: 32606756] (IF/IHC, Human)	IF/IHC	Human
Kayalar O, Oztay F, Ongen HG Gastrin-releasing peptide induces fibrotic response in MRC5s and proliferation in A549s Cell Commun. Signal 2020-06-18 [PMID: 32552754] (WB, Human)	WB	Human
Fultang N, Illendula A, Chen B et al. Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3 beta activity PLoS ONE 2019-05-31 [PMID: 31150511] (WB, Human)	WB	Human
Jung CK, Jung SH, Yim SH et al. Predictive microRNAs for lymph node metastasis in endoscopically resectable submucosal colorectal cancer. Oncotarget. 2016-05-31 [PMID: 27096956] (IF/IHC, Human)	IF/IHC	Human
Lin CW Jan MS Kuo JH. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. [PMID: 26158199]
Lim S, Becker A, Zimmer A et al. SNAI1-mediated epithelial-mesenchymal transition confers chemoresistance and cellular plasticity by regulating genes involved in cell death and stem cell maintenance. PLoS One. 2013-06-17 [PMID: 23799116] Details: Wnt-5A (IMG-6075). WB: Fig 5H. MCF10A cells stably transfected with SNAI1. Note: The specificity of the Wnt-5A was validated in Wnt5a treated MCF10A-SNAI1 by WB in Fig 5H.
Shi Y, Shu J, Gelman BB et al. Wnt signaling in the pathogenesis of human HIV-associated pain syndromes. J Neuroimmune Pharmacol. 2013-09-01 [PMID: 23737037] Details: Wnt-5a (IMG-6075). WB: Fig 1, human postmortem lumbar spinal cord dorsal horn (SDH). Wnt5a was detected between the 35 and 55 kDa markers primarily as a single band or as two bands. IHC (P): Fig 4, SDH. Wnt5a signals formed bright spots in the SDS and wer
Rashid ST, Humphries JD, Byron A et al. Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver. J Proteome Res. 2012-08-03 [PMID: 22694338] Details: Wnt-5a (IMG-6075). IHC (paraffin): human fibrotic liver (Figs 5C, 5D, S2E-H), mouse fibrotic liver (Figs 6A,6B, S3A-D), normal mouse liver (Fig S4D).
Shi Y, Fu Y, Tong W et al. Uniaxial mechanical tension promoted osteogenic differentiation of rat tendon-derived stem cells (rTDSCs) via the Wnt5a-RhoA pathway. J Cell Biochem. 2012-10-01 [PMID: 22615126] (WB) Details: Wnt-5a (IMG-6075). WB: Figs 1A, 1C. Rat tendon-derived stem cells (rTDSCs). Wnt5a was detected at ~41kDa. Note: The specificity of the Wnt-5A was validated in Wnt5a-siRNA transfected rTDSCs by WB in Figs 1A, 1C.	WB
Siar CH, Nagatsuka H, Han PP et al. Differential expression of canonical and non-canonical Wnt ligands in ameloblastoma. J Oral Pathol Med. 2012-04-01 [PMID: 22077561] (Human) Details: Wnt-5A (IMG-6075). IHC(P): Human ameloblastomas (Tables 1,2; Figs 1I, 5I, 4C, 4D). Human ameloblastomas were primarily negative for Wnt-5A expression.		Human
Olivares-Navarrete R, Hyzy SL, Hutton DL et al. Role of non-canonical Wnt signaling in osteoblast maturation on microstructured titanium surfaces. Acta Biomater. 2011-06-01 [PMID: 21352958] (Human) Details: Wnt-5A (IMG-6075). Functional Assays: Human osteoblast-like MG63 cells were treated with the Wnt-5A IMG-6075A pAb [2.5 ug/ml (Figs 7, 8)]. See publication for details.		Human
Rao Q, Liu XH, Zhou HB et al. Expression analysis of Wnt-5a in renal epithelial neoplasms: distinguishing renal oncocytoma from a wide spectrum of renal cell carcinomas. Tumori. 2010-03-01 [PMID: 20572590] (IHC-P) Details: Wnt5a (IMG-6075A). IHC (paraffin): Normal kidney, renal epithelial neoplasm, papillary renal cell carcinoma, and mucinous tubular spindle cell carcinoma, Fig 1.	IHC-P
Qian W, Yan Q, Jiang X Et al. Study of lncRNA TUG1/miR-320 in EPC Transplantation to Improve Lower Limb Ischemia and Promote Angiogenesis in Mice Research Square 2021-11-01 (WB, Mouse)	WB	Mouse
Sheng J Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts Thesis
Cameron S Anti-Cancer and Stress Response Pathway Effects of Nanosilver and Sodium Ascorbate Carleton University 2022-07-11 (WB, Human)	WB	Human
Show All 16 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	IHC-Fr	Petaurus breviceps (marsupial)	02/25/2019	View Summary Application Immunohistochemistry-Frozen Sample Tested Skin frozen tissue,Skin tissue Species Petaurus breviceps (marsupial) Lot C-1 Comments Comments 1:100 dilution. We cryo-sectioned fixed tissue (12um slices) in OCT, washed samples for 10min in PBT (PBS + 0.1% tween), blocked the sample for 1hr in 3%BSA/PBS and then incubated with the antibody overnight at 4C. The next day we washed 3x for 10min in PBT and incubated for one hr in Alexa488 (1:500), washed 3x10min in PBS and coverslipped.

Array NBP2-24752

• Wnt-5a Antibodies
• Wnt-5a ELISA Kits
• Wnt-5a Lysate
• Wnt-5a Protein
• Wnt-5a Proteins and Enzymes