ROR alpha/NR1F1 Antibody

The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: ICC/IF, IHC, IHC-P, KD, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-52813	Applications	Species
Yu W, Du J, Peng L, Zhang T ROR? overexpression reduced interleukin-33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis Immunity, inflammation and disease 2023-10-01 [PMID: 37904695] (KD, IHC, WB, ICC/IF, Human, Mouse)	KD, IHC, WB, ICC/IF	Human, Mouse
Guerra M, Medici V, Weatheritt R et al. Fetal exposure to valproic acid dysregulates the expression of autism-linked genes in the developing cerebellum Translational psychiatry 2023-04-05 [PMID: 37019889] (WB, Mouse)	WB	Mouse
Li J, Liu H, Wang X et al. Melatonin ameliorates Parkinson's disease via regulating microglia polarization in a ROR alpha-dependent pathway NPJ Parkinson's disease 2022-07-08 [PMID: 35803929] (IHC-P, Mouse)	IHC-P	Mouse
Suyama K, Silagi ES, Choi H et al. Circadian factors BMAL1 and RORalpha control HIF-1alpha transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget 2016-04-26 [PMID: 27049729] (WB)	WB
Benderdour M, Fahmi H, Beaudet F et al. Nuclear receptor retinoid-related orphan receptor [alpha]1 modulates the metabolic activity of human osteoblasts. J Cell Biochem 112(8):2160-2169. 2011-08-01 [PMID: 21480365]

Array NBP1-52813

• ROR alpha/NR1F1 Antibodies
• ROR alpha/NR1F1 ELISA Kit
• ROR alpha/NR1F1 Lysates
• ROR alpha/NR1F1 Protein