WNK1 Antibody

Images

 
Immunohistochemistry: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of non-small cell carcinoma of the lung.
Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of formalin-fixed, paraffin-embedded human skeletal muscle after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of formalin-fixed, paraffin-embedded human skin melanoma after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of formalin-fixed, paraffin-embedded human lung, non-small cell carcinoma, after heat-induced antigen retrieval.
Immunohistochemistry: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of brain, glioblastoma.
Immunohistochemistry: WNK1 Antibody [NBP3-14518] - Immunohistochemistry of ovary carcinoma

Product Details

Summary
Reactivity Hu, Mu, Rt, Bt, Eq, Ha, Pm, Pm, RbSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

WNK1 Antibody Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 17 amino acid peptide near C-Terminus of human WNK1.
Epitope
C-Terminus
Specificity
Human WNK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (100%), Rat (100%), Hamster (100%), Bat (100%), Primate (100%), Equine (100%), Monkey (100%), Rabbit (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
WNK1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
.

Reactivity Notes

Expected reactivity based on percent sequence identity: Bovine (88%)

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for WNK1 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • Erythrocyte 65 kDa protein
  • HSAN2hereditary sensory neuropathy, type II
  • HSN2MGC163339
  • hWNK1
  • KDP
  • KDPMGC163341
  • KIAA0344
  • Kinase deficient protein
  • p65
  • PHA2C
  • PRKWNK1
  • PRKWNK1PSK
  • prostate-derived sterile 20-like kinase
  • Protein kinase lysine-deficient 1
  • Protein kinase with no lysine 1
  • protein kinase, lysine deficient 1
  • serine/threonine-protein kinase WNK1
  • WNK lysine deficient protein kinase 1
  • WNK1

Background

WNK lysine deficient protein kinase 1 (WNK1) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. WNK1 is responsible for controling Na+ and Cl- ion transport by inhibiting the activity of other related protein kinases, such as WNK4.

WNK1 mutations have been associated with Gordon hyperkalemia-hypertension syndrome (pseudohypoaldosteronism type II) and congenital sensory neuropathy.

WNK1 is also known as Human Accelerated Region 5, and is thought to have played a key role in differentiating humans from apes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional WNK1 Products

Array NBP3-14518

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Bioinformatics

Gene Symbol WNK1