WNK1 Antibody Summary
Description |
Product can be stored undiluted at 4C for up to 1 month. |
Immunogen |
Synthetic 17 amino acid peptide near C-Terminus of human WNK1. |
Epitope |
C-Terminus |
Specificity |
Human WNK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Predicted Species |
Mouse (100%), Rat (100%), Hamster (100%), Bat (100%), Primate (100%), Equine (100%), Monkey (100%), Rabbit (100%). Backed by our 100% Guarantee. |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
WNK1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin
|
Application Notes |
. |
Reactivity Notes
Expected reactivity based on percent sequence identity: Bovine (88%)
Packaging, Storage & Formulations
Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.1% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for WNK1 Antibody
Background
WNK lysine deficient protein kinase 1 (WNK1) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. WNK1 is responsible for controling Na+ and Cl- ion transport by inhibiting the activity of other related protein kinases, such as WNK4.
WNK1 mutations have been associated with Gordon hyperkalemia-hypertension syndrome (pseudohypoaldosteronism type II) and congenital sensory neuropathy.
WNK1 is also known as Human Accelerated Region 5, and is thought to have played a key role in differentiating humans from apes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for WNK1 Antibody (NBP3-14518) (0)
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