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Versican Antibody

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Immunohistochemistry-Paraffin: Versican Antibody [NBP1-85432] - Staining of human uterine cervix shows strong positivity in the extracellular matrix.
Immunohistochemistry-Paraffin: Versican Antibody [NBP1-85432] - Staining of human cerebral cortex shows strong positivity in neuropil.
Immunohistochemistry-Paraffin: Versican Antibody [NBP1-85432] - Staining of human stomach shows moderate positivity in extracellular matrix.
Immunohistochemistry-Paraffin: Versican Antibody [NBP1-85432] - Staining of human tonsil shows no positivity as expected.
Biological Strategies: Western Blot: Versican Antibody [NBP1-85432] - Treatment of CAFs with combined cytokines or cancer cell-derived secretomes affects ECM protein expression. Western blot showing the effects ...read more
Treatment of CAFs with combined cytokines or cancer cell-derived secretomes affects ECM protein expression(A) Western blot showing the effects of bFGF, EGF & TGF-beta 1 treatment (10 ng/ml) on the expression of ...read more
Treatment of CAFs with combined cytokines or cancer cell-derived secretomes affects ECM protein expression(A) Western blot showing the effects of bFGF, EGF & TGF-beta 1 treatment (10 ng/ml) on the expression of ...read more
Immunohistochemistry: Versican Antibody [NBP1-85432] - Immunohistochemical staining of stromal protein expression in DCIS with sclerotic or myxoid stromaMicrophotographs displaying HE staining (A-B), & IHC staining for ...read more
Immunohistochemistry: Versican Antibody [NBP1-85432] - Immunohistochemical staining of stromal protein expression in DCIS with sclerotic or myxoid stromaMicrophotographs displaying HE staining (A-B), & IHC staining for ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
   

Biological Strategies

     

Order Details

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Versican Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VCAN
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Versican Protein (NBP1-85432PEP)
Publications
Read Publications using
NBP1-85432 in the following applications:

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:34178974).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Versican Antibody

  • Chondroitin sulfate proteoglycan 2WGN
  • Chondroitin sulfate proteoglycan core protein 2
  • CSPG2
  • CSPG2DKFZp686K06110
  • ERVR
  • GHAP
  • Glial hyaluronate-binding protein
  • Large fibroblast proteoglycan
  • PG-M
  • PG-MWGN1
  • VCAN
  • versican core protein
  • versican proteoglycan
  • Versican

Background

Versican is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Versican Antibody (NBP1-85432)(7)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: FLOW, ICC/IF, IF/IHC, IHC-P.


Filter By Application
FLOW
(1)
ICC/IF
(1)
IF/IHC
(2)
IHC-P
(2)
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Filter By Species
Human
(4)
Mouse
(1)
All Species
Showing Publications 1 - 7 of 7.
Publications using NBP1-85432 Applications Species
Li J, Sina AAI, Antaw F et al. Digital Decoding of Single Extracellular Vesicle Phenotype Differentiates Early Malignant and Benign Lung Lesions Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022-11-17 [PMID: 36394090] (FLOW, Human) FLOW Human
Ghorbani S, Jelinek E, Jain R et al. Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination Nature communications 2022-05-04 [PMID: 35508608] (ICC/IF, IHC-P, Human) ICC/IF, IHC-P Human
Yoshioka H, Suzuki A, Iwaya C, Iwata J Suppression of microRNA 124-3p and microRNA 340-5p ameliorates retinoic acid-induced cleft palate in mice Development (Cambridge, England) 2022-05-01 [PMID: 35420127]
Yoshioka H, Mikami Y, Ramakrishnan SS et al. MicroRNA-124-3p Plays a Crucial Role in Cleft Palate Induced by Retinoic Acid Frontiers in cell and developmental biology 2021-06-09 [PMID: 34178974] (IHC-P, Mouse) IHC-P Mouse
Cai WY, Dong ZN, Fu XT et al. Identification of a Tumor Microenvironment-relevant Gene set-based Prognostic Signature and Related Therapy Targets in Gastric Cancer Theranostics 2020-07-09 [PMID: 32754268] (IF/IHC, Human) IF/IHC Human
Yang Z, Ma S, Cao R et al. CD49fhigh Defines A Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance J. Invest. Dermatol. 2019-09-05 [PMID: 31494092]
Van Bockstal M, Lambein K, Van Gele M et al. Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF--beta1 regulates cancer cell spreading but not adhesion. Oncoscience 2014-01-01 [PMID: 25593993] (IF/IHC, Human) IF/IHC Human

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Bioinformatics

Gene Symbol VCAN
Entrez
Uniprot