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VEGFR1/Flt-1 Antibody

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Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human placenta stained with VEGFR1/Flt-1 antibody (NB100-685).
Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human placenta stained with VEGFR1/Flt-1 antibody (NB100-685).
Immunohistochemistry: VEGF R1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human angiosarcoma stained with Flt-1.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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VEGFR1/Flt-1 Antibody Summary

Immunogen
Synthetic peptide: C-AELERKIACCSPPPDYN, corresponding to amino acids 1312-1328 of human VEGF Receptor 1 (C-terminus).
Localization
Cytoplasmic
Marker
Endothelial Cell Marker
Specificity
This reacts with a 180 kD protein, known as VEGFR1/Flt-1 or vascular endothelial growth factor receptor 1. VEGFR1/Flt-1 is a cell membrane receptor kinase. VEGFR1/Flt-1 has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FLT1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:25-1:50
  • Immunohistochemistry-Frozen 1:50-1:100
  • Immunohistochemistry-Paraffin 1:25-1:50
Application Notes
IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.
Publications
Read Publications using NB100-685.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4), 0.2% BSA, Tween-20
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for VEGFR1/Flt-1 Antibody

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT
  • FLT1
  • Flt-1
  • Fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
  • FRT
  • Tyrosine-protein kinase FRT
  • Tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • Vascular permeability factor receptor
  • VEGF R1
  • VEGFR1
  • VEGFR-1

Background

The receptor for VEGF, VEGFB and PGF has tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis. VEGFR 1 is a cell membrane receptor kinase. It has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for VEGFR1/Flt-1 Antibody (NB100-685)(2)

We have publications tested in 1 confirmed species: Human.


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Bioinformatics

Gene Symbol FLT1
Entrez
Uniprot