Recombinant Human VAMP-2 His Protein

Synaptobrevin 2(Vehicle-associated membrane, VAMP2), which is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. Synaptobrevin 2 is predominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein (residues 1-89) forms a specific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NBC1-18335	Applications	Species
Goossens J, Cervantes González A, Dewit N et al. Evaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimer's disease continuum Alzheimer's research & therapy 2023-10-28 [PMID: 37898760] (WB)	WB
Das S, Goossens J, Jacobs D et al. Synaptic biomarkers in the cerebrospinal fluid associate differentially with classical neuronal biomarkers in patients with Alzheimer's disease and frontotemporal dementia Alzheimer's research & therapy 2023-03-24 [PMID: 36964594] (Human)		Human

Array NBC1-18335

• VAMP-2 Antibodies
• VAMP-2 ELISA Kits
• VAMP-2 Lysate
• VAMP-2 Proteins