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ULK1 Antibody [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-41217AF350
Alexa Fluor 405
NBP2-41217AF405
Alexa Fluor 488
NBP2-41217AF488
Alexa Fluor 532
NBP2-41217AF532
Alexa Fluor 594
NBP2-41217AF594
Alexa Fluor 647
NBP2-41217AF647
Alexa Fluor 700
NBP2-41217AF700
Alexa Fluor 750
NBP2-41217AF750
Biotin
NBP2-41217B
CoraFluor 1
NBP2-41217CL1
DyLight 405
NBP2-41217V
DyLight 488
NBP2-41217G
DyLight 550
NBP2-41217R
DyLight 594
NBP2-41217DL594
DyLight 650
NBP2-41217C
DyLight 680
NBP2-41217FR
DyLight 755
NBP2-41217IR
FITC
NBP2-41217F
HRP
NBP2-41217H
Janelia Fluor 525
NBP2-41217JF525
Janelia Fluor 549
NBP2-41217JF549
Janelia Fluor 646
NBP2-41217JF646
Janelia Fluor 669
NBP2-41217JF669
PerCP
NBP2-41217PCP
Unconjugated
NBP2-41217
mFluor Violet 450 SE
NBP2-41217MFV450
mFluor Violet 500 SE
NBP2-41217MFV500
mFluor Violet 610 SE
NBP2-41217MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-41217
BSA Free
NBP2-41217
BSA Free
NBP2-41217-0.025mg
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ULK1 Antibody [DyLight 350] Summary

Immunogen
Antibody was raised against a 16 amino acid peptide near the center of human ULK1 . The immunogen is located within amino acids 350 - 400 of ULK1. Amino Acid Squence: CDLVAEAPSAKPPPDSL
Specificity
Two alternatively spliced transcript variants encoding different isoforms have been identified. ULK1 antibody is predicted to not cross-react with ULK2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ULK1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ULK1 Antibody [DyLight 350]

  • ATG1 autophagy related 1 homolog
  • ATG1
  • ATG1A
  • EC 2.7.11
  • EC 2.7.11.1
  • FLJ38455
  • FLJ46475
  • hATG1
  • KIAA0722
  • serine/threonine-protein kinase ULK1
  • ULK1
  • unc-51 (C. elegans)-like kinase 1
  • UNC51
  • Unc51.1
  • unc-51-like kinase 1 (C. elegans)
  • Unc-51-like kinase 1

Background

ULK1 belongs to the serine/threonine protein kinase family. It is involved in axon growth and plays an essential role in neurite branching during sensory axon outgrowth. Knockdown of ULK1 results in impaired endocytosis of nerve growth factor (NGF), excessive axon arborization, and severely stunted axon elongation indicating that ULK1 mediates a non clathrin coated endocytosis in sensory growth cones. Knockdown of ULK1 also inhibits the autophagic response. It appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy related (Atg) proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ULK1 Antibody
[DyLight 350]
NBP2-41217UV
ULK1 Antibody [DyLight 350]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, ICC/IF

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ULK1