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TXNIP Antibody (JY2) - Azide and BSA Free

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Western Blot: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - TXNIP expression in Raji (1), K562 (2), KG1 (3), MRC5 (4), IC2Tr (5), HEL (6), P19 (7) and WR19L (8). Image from the standard format of this ...read more
Immunocytochemistry: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - Formalin fixed and paraffin embedded tissue section of mouse kidney using TXNIP antibody (clone JY2) at 1:250 dilution. The signal was ...read more
Immunohistochemistry: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - Formalin fixed and paraffin embedded tissue section of mouse kidney using TXNIP antibody (clone JY2) at 1:100 dilution. The signal was ...read more
Flow Cytometry: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - An intracellular stain was performed on RH-30 cells with TXNIP (JY2) Antibody NBP1-54578F (blue) and a matched isotype control (orange). Cells ...read more
Western Blot: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - Hepa1 lysates probed with anti-TXNIP (JY2) at 1:2K. Cells were transfected with either empty vector or mouse TXNIP expression vector (MYC/DDK ...read more
Immunohistochemistry: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - TXNIP in mouse brain. Antibody dilution: 1:100, incubated overnight in 5%BSA + 0.2% Triton X 100. Image from verified customer review. Image ...read more
Immunoprecipitation: TXNIP Antibody (JY2) - Azide and BSA Free [NBP2-81001] - Txnip/VDUP1 from Raji with NBP1-54578 (1) or mouse IgG1 (2). Image from the standard format of this antibody.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, Func, ICC/IF, IHC, IP, CyTOF-ready, KO
Clone
JY2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

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TXNIP Antibody (JY2) - Azide and BSA Free Summary

Immunogen
Human recombinant TXNIP
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TXNIP
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2-5 ug/0.1x10^6 cells
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen reported by customer review
  • Immunohistochemistry-Paraffin 1:100-1:500
  • Immunoprecipitation 5x10^6 cells
  • Knockout Validated
  • Proximity Ligation Assay
  • Western Blot 1:1000

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for TXNIP Antibody (JY2) - Azide and BSA Free

  • HHCPA78
  • THIF
  • thioredoxin binding protein 2
  • thioredoxin interacting protein
  • Thioredoxin-binding protein 2
  • thioredoxin-interacting protein
  • upregulated by 1,25-dihydroxyvitamin D-3
  • VDUP1EST01027
  • Vitamin D3 up-regulated protein 1

Background

Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that TXNIP plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TXNIP Antibody (NBP2-81001) (0)

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Bioinformatics

Gene Symbol TXNIP