TRIM Antibody (TRIM-04) - BSA Free

TRIM (TCR-Interactin molecule) stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. Sequence analysis predicts that TRIM is a 186-amino acid type III transmembrane protein containing an 8-amino acid extracellular domain, which includes a cys residue, and a 19-amino acid transmembrane region that lacks charged residues. The intracellular portion possesses 4 potential phosphorylation sites and 8 tyrosine residues. It is strongly expressed in adult thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level). It can be found in the foetal thymus at weeks 17-24 of gestation but is undetectable in bone marrow and foetal liver.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: FLOW.

Showing Publication 1 - 1 of 1.

Publication using NB500-485	Applications	Species
Jahan AS, Lestra M, Swee LK et al. Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling. Proc. Natl. Acad. Sci. U.S.A. 2016-02-09 [PMID: 26811477] (FLOW, Human) Details: This citation used the PE version of this antibody.	FLOW	Human

Array NB500-485

• TRIM Antibodies
• TRIM Lysate
• TRIM Proteins