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Transferrin Antibody

Images

 
Independent Antibodies: Western Blot: Transferrin Antibody [NBP1-87221] - Analysis using Anti-TF antibody NBP1-87221 (A) shows similar pattern to independent antibody NBP1-87222 (B).
Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human lymph node.
Western Blot: Transferrin Antibody [NBP1-87221] - Analysis in human cell line HepG2.
Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human plasma shows moderate positivity.
Independent Antibodies: Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human colon, liver, lymph node and ovary using Anti-TF antibody NBP1-87221 (A) shows similar protein ...read more
Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human ovary.
Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human colon.
Immunohistochemistry-Paraffin: Transferrin Antibody [NBP1-87221] - Staining of human liver using Anti-TF antibody NBP1-87221.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

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Transferrin Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: KDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TF
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Transferrin Protein (NBP1-87221PEP)
Publications
Read Publication using NBP1-87221.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Transferrin Antibody

  • Beta-1 metal-binding globulin
  • DKFZp781D0156
  • EC 3.4.21
  • PRO1557
  • PRO2086
  • Serotransferrin
  • Siderophilin
  • TF
  • Transferrin

Background

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Transferrin Antibody (NBP1-87221)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Transferrin Products

Research Areas for Transferrin Antibody (NBP1-87221)

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Blogs on Transferrin.

Transferrin: "Ironing" out the Details of Cellular Anemia
Transferrin is a protein found in the blood plasma, a glycoprotein that is specific for controlling free iron in the bodies' biological fluids. Transferrin has two binding sites that are specific for very tight and reversible iron binding. The binding...  Read full blog post.

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Bioinformatics

Gene Symbol TF