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TIM-1/KIM-1/HAVCR Antibody (3B3) [Alexa Fluor® 350]

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TIM-1/KIM-1/HAVCR Antibody (3B3) [Alexa Fluor® 350] [NBP2-81119AF350] - Vial of Alexa Fluor 350 conjugated antibody. Alexa Fluor 350 is optimally excited at 346 nm by the UV laser (350 or 355 nm) and has an emission maximum of 442 nm.
TIM-1/KIM-1/HAVCR Antibody (3B3) [Alexa Fluor® 350] [NBP2-81119AF350] - Vial of Alexa Fluor 350 conjugated antibody. Alexa Fluor 350 is optimally excited at 346 nm by the UV laser (350 or 355 nm) and has an ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, Flow, Func, ICC/IF, IHC, B/N, SPR
Clone
3B3
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NBP2-81119AF405
Alexa Fluor 488
NBP2-81119AF488
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NBP2-81119AF532
Alexa Fluor 594
NBP2-81119AF594
Alexa Fluor 647
NBP2-81119AF647
Alexa Fluor 700
NBP2-81119AF700
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NBP2-81119AF750
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NBP2-81119B
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DyLight 350
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DyLight 405
NBP2-81119V
DyLight 488
NBP2-81119G
DyLight 550
NBP2-81119R
DyLight 594
NBP2-81119DL594
DyLight 650
NBP2-81119C
DyLight 680
NBP2-81119FR
DyLight 755
NBP2-81119IR
FITC
NBP2-81119F
HRP
NBP2-81119H
Janelia Fluor 525
NBP2-81119JF525
Janelia Fluor 549
NBP2-81119JF549
Janelia Fluor 646
NBP2-81119JF646
Janelia Fluor 669
NBP2-81119JF669
PE
NBP2-81119PE
PerCP
NBP2-81119PCP
Unconjugated
NBP2-81119-0.2mg
mFluor Violet 450 SE
NBP2-81119MFV450
mFluor Violet 500 SE
NBP2-81119MFV500
mFluor Violet 610 SE
NBP2-81119MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-81119-0.2mg
Azide and BSA Free
NBP2-81119-0.2mg
Azide and BSA Free
NBP2-81119-0.025mg
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TIM-1/KIM-1/HAVCR Antibody (3B3) [Alexa Fluor® 350] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was raised by immunising female Lewis strain rats (Harlan Sprague-Dawley) subcutaneously with mouse TIM-1/KIM-1/HAVCR-Ig in complete Freund's adjuvant (CFA), followed by multiple 'boosting' with mouse TIM-1/KIM-1/HAVCR-Ig in PBS.
Specificity
This antibody is specific for murine TIM-1/KIM-1/HAVCR, a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. TIM-1/KIM-1/HAVCR has been found on activated CD4+ T cells, mast cells, and a subset of B cells. TIM-1/KIM-1/HAVCR is involved in renal injury, tissue homeostasis, and T cell costimulation, and promotes the differentiation of Th2 cells and the production of IL-4. TIM-1/KIM-1/HAVCR can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
HAVCR1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Block/Neutralize
  • ELISA
  • Flow Cytometry
  • Functional
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Surface Plasmon Resonance
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TIM-1/KIM-1/HAVCR Antibody (3B3) [Alexa Fluor® 350]

  • CD365
  • HAVCR1
  • HAVCR-1
  • HAVCRT cell immunoglobin domain and mucin domain protein 1
  • hepatitis A virus cellular receptor 1
  • Kidney injury molecule 1
  • KIM1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIM1
  • TIM-1
  • TIM-1TIM
  • TIM1TIMD-1
  • TIMD1T-cell membrane protein 1

Background

TIM 1 is a transmembrane protein containing immunoglobulin domain and mucin-like domain; it is developmentally expressed at very high levels in the blastocyst. TIM 1 binds hepatitis virus in humans and is expressed on activated CD4+ lymphocytes especially on Th2 cells and has been implicated to play a critical role in the development of atopic disease (in particular airway hyperreactivity) and other Th2-biased immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TIM-1/KIM-1/HAVCR
Antibody (3B3) [Alexa ...
NBP2-81119AF350
TIM-1/KIM-1/HAVCR Antibody (3B3) [Alexa Fluor® 350]
Species: Mu
Applications: ELISA, Flow, Func, ICC/IF, IHC, B/N, SPR

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HAVCR1