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Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric)

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ELISA: Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric) [NBP3-08186] - Samples were spiked with high concentrations of Rat Thrombomodulin/BDCA-3 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.
ELISA: Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric) [NBP3-08186] - Samples were spiked with high concentrations of Rat Thrombomodulin/BDCA-3 and diluted with Reference Standard & Sample Diluent to produce samples ...read more
ELISA: Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric) [NBP3-08186] - Standard Curve Reference

Product Details

Summary
Reactivity RtSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, Plasma, Cell supernatant
Standard Curve Range
93.75 - 6000 pg/mL
Sensitivity
56.25 pg/mL

Order Details

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Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric) Summary

Standard Curve Range
93.75 - 6000 pg/mL
Sensitivity
56.25 pg/mL
Assay Type
Sandwich-ELISA
Inter-Assay
%CV < 5.72
Intra-Assay
%CV < 6.82
Spike Recovery
84 - 104%
Kit Type
ELISA Kit (Colorimetric)
Gene
THBD

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Micro ELISA Plate (Dismountable) - 1 EA, Reference Standard - 2 vials, Concentrated Biotinylated Detection Ab (100X) - 120 uL, Concentrated HRP Conjugate (100X) - 120 uL, Reference Standard & Sample Diluent - 20 mL, Biotinylated Detection Ab Diluent - 14

Alternate Names for Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric)

  • BDCA3
  • BDCA-3
  • CD141 antigen
  • CD141
  • Fetomodulin
  • THBD
  • THRM
  • Thrombomodulin
  • TM

Background

CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Thrombomodulin - A multifunctional protein with roles in inflammation and coagulation
Thrombomodulin, also known as BDCA-3, is a glycosylated transmembrane protein present on the surface of vascular endothelial cells. Thrombomodulin is a high-affinity receptor for thrombin, a key protein in the coagulation cascade. Formation of the...  Read full blog post.
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Product PDFs

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  Manual - Rat Thrombomodulin/BDCA-3 ELISA Kit (Colorimetric)
  PDF Datasheet
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Bioinformatics

Gene Symbol THBD