Thimet Oligopeptidase/THOP1 Antibody (4D6) [DyLight 650] Summary
Immunogen |
A synthetic peptide corresponding to residues 56-72 of human Thimet Oligopeptidase. [UniProt# P52888] |
Localization |
Cytoplasmic |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
THOP1 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Thimet Oligopeptidase/THOP1 Antibody (4D6) [DyLight 650]
Background
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enxymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for Thimet Oligopeptidase/THOP1 Antibody (NB400-146C) (0)
Secondary Antibodies
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