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TGF-beta 1 Antibody (SRK181) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
SRK181
Clonality
Monoclonal
Host
Human
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28701AF350
Alexa Fluor 405
NBP3-28701AF405
Alexa Fluor 488
NBP3-28701AF488
Alexa Fluor 532
NBP3-28701AF532
Alexa Fluor 594
NBP3-28701AF594
Alexa Fluor 647
NBP3-28701AF647
Alexa Fluor 700
NBP3-28701AF700
Alexa Fluor 750
NBP3-28701AF750
Allophycocyanin
NBP3-28701APC
Biotin
NBP3-28701B
CoraFluor 1
NBP3-28701CL1
DyLight 350
NBP3-28701UV
DyLight 405
NBP3-28701V
DyLight 488
NBP3-28701G
DyLight 550
NBP3-28701R
DyLight 594
NBP3-28701DL594
DyLight 650
NBP3-28701C
DyLight 680
NBP3-28701FR
DyLight 755
NBP3-28701IR
FITC
NBP3-28701F
HRP
NBP3-28701H
Janelia Fluor 525
NBP3-28701JF525
Janelia Fluor 646
NBP3-28701JF646
Janelia Fluor 669
NBP3-28701JF669
PE
NBP3-28701PE
PerCP
NBP3-28701PCP
Unconjugated
NBP3-28701-100ug
mFluor Violet 450 SE
NBP3-28701MFV450
mFluor Violet 500 SE
NBP3-28701MFV500
mFluor Violet 610 SE
NBP3-28701MFV610
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TGF-beta 1 Antibody (SRK181) [Janelia Fluor® 549] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
TGFb1
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
TGFB1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TGF-beta 1 Antibody (SRK181) [Janelia Fluor® 549]

  • CEDLAP
  • DPD1
  • latency-associated peptide
  • TGF beta
  • TGF beta1
  • TGFB
  • TGFB1
  • TGF-beta 1 protein
  • TGFbeta 1
  • TGF-beta 1
  • TGFbeta
  • TGF-beta-1
  • transforming growth factor beta-1
  • transforming growth factor, beta 1

Background

TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TGF-beta 1
Antibody (SRK181) [Ja ...
NBP3-28701JF549
TGF-beta 1 Antibody (SRK181) [Janelia Fluor® 549]
Species: Hu
Applications: ELISA, Flow, Func

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Secondary Antibodies

 

Isotype Controls

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TGF-beta 1 - a versatile signaling molecule with roles in development and disease
The transforming growth factor-beta (TGF-beta) family consists of a wide variety of signaling proteins with roles in development. TGF-beta signaling controls growth, differentiation, and immune responses and is often misregulated in cancer. TGF-beta ...  Read full blog post.
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Bioinformatics

Gene Symbol TGFB1