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TGF-beta 1 Antibody (fresolimumab) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
fresolimumab
Clonality
Monoclonal
Host
Human
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28822AF350
Alexa Fluor 405
NBP3-28822AF405
Alexa Fluor 488
NBP3-28822AF488
Alexa Fluor 532
NBP3-28822AF532
Alexa Fluor 594
NBP3-28822AF594
Alexa Fluor 647
NBP3-28822AF647
Alexa Fluor 700
NBP3-28822AF700
Alexa Fluor 750
NBP3-28822AF750
Allophycocyanin
NBP3-28822APC
Biotin
NBP3-28822B
DyLight 350
NBP3-28822UV
DyLight 405
NBP3-28822V
DyLight 488
NBP3-28822G
DyLight 550
NBP3-28822R
DyLight 594
NBP3-28822DL594
DyLight 650
NBP3-28822C
DyLight 680
NBP3-28822FR
DyLight 755
NBP3-28822IR
FITC
NBP3-28822F
HRP
NBP3-28822H
Janelia Fluor 525
NBP3-28822JF525
Janelia Fluor 549
NBP3-28822JF549
Janelia Fluor 585
NBP3-28822JF585
Janelia Fluor 635
NBP3-28822JF635
Janelia Fluor 646
NBP3-28822JF646
Janelia Fluor 669
NBP3-28822JF669
PE
NBP3-28822PE
PerCP
NBP3-28822PCP
Unconjugated
NBP3-28822-100ug
mFluor Violet 450 SE
NBP3-28822MFV450
mFluor Violet 500 SE
NBP3-28822MFV500
mFluor Violet 610 SE
NBP3-28822MFV610
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TGF-beta 1 Antibody (fresolimumab) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
TGFb1
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
TGFB1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for TGF-beta 1 Antibody (fresolimumab) [CoraFluor™ 1]

  • CEDLAP
  • DPD1
  • latency-associated peptide
  • TGF beta
  • TGF beta1
  • TGFB
  • TGFB1
  • TGF-beta 1 protein
  • TGFbeta 1
  • TGF-beta 1
  • TGFbeta
  • TGF-beta-1
  • transforming growth factor beta-1
  • transforming growth factor, beta 1

Background

TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TGF-beta 1
Antibody (fresolimuma ...
NBP3-28822CL1
TGF-beta 1 Antibody (fresolimumab) [CoraFluor™ 1]
Species: Hu
Applications: ELISA, Flow, Func

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Secondary Antibodies

 

Isotype Controls

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TGF-beta 1 - a versatile signaling molecule with roles in development and disease
The transforming growth factor-beta (TGF-beta) family consists of a wide variety of signaling proteins with roles in development. TGF-beta signaling controls growth, differentiation, and immune responses and is often misregulated in cancer. TGF-beta ...  Read full blog post.
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Bioinformatics

Gene Symbol TGFB1