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TGF-beta 1 Antibody (1018746) [FITC]

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TGF-beta 1 Antibody (1018746) [FITC] [FAB10502F] - Vial of FITC conjugated antibody. FITC is optimally excited at 498 nm by the Blue laser (488 nm) and has an emission maximum of 519 nm.
TGF-beta 1 Antibody (1018746) [FITC] [FAB10502F] - Vial of FITC conjugated antibody. FITC is optimally excited at 498 nm by the Blue laser (488 nm) and has an emission maximum of 519 nm.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
1018746
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC10502U-100UG
Alexa Fluor 405
IC10502V-100UG
Alexa Fluor 488
IC10502G-100UG
Alexa Fluor 532
FAB10502X
Alexa Fluor 594
IC10502T-100UG
Alexa Fluor 647
IC10502R-100UG
Alexa Fluor 700
IC10502N-100UG
Alexa Fluor 750
IC10502S-100UG
Allophycocyanin
FAB10502A
Biotin
FAB10502B
DyLight 350
FAB10502D
DyLight 405
FAB10502E
DyLight 488
FAB10502K
DyLight 550
FAB10502L
DyLight 594
FAB10502M
DyLight 650
FAB10502W
DyLight 680
FAB10502Y
DyLight 755
FAB10502Z
HRP
FAB10502H
Janelia Fluor 549
FAB10502I
Janelia Fluor 646
FAB10502J
PE
FAB10502P
PerCP
FAB10502C
Unconjugated
MAB10502-100
mFluor Violet 450 SE
FAB10502MFV450
mFluor Violet 500 SE
FAB10502MFV500
mFluor Violet 610 SE
FAB10502MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10502-100
Carrier Free
MAB10502-100
Carrier Free
MAB10502-SP
Carrier Free
IC10502V-100UG
Carrier Free
IC10502U-100UG
Carrier Free
IC10502T-100UG
Carrier Free
IC10502S-100UG
Carrier Free
IC10502R-100UG
Carrier Free
IC10502N-100UG
Carrier Free
IC10502G-100UG
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TGF-beta 1 Antibody (1018746) [FITC] Summary

Immunogen
Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein
Ala279-Ser390
Accession # P01137
Specificity
Detects human TGF-beta 1 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for TGF-beta 1 Antibody (1018746) [FITC]

  • CEDLAP
  • DPD1
  • latency-associated peptide
  • TGF beta
  • TGF beta1
  • TGFB
  • TGFB1
  • TGF-beta 1 protein
  • TGFbeta 1
  • TGF-beta 1
  • TGFbeta
  • TGF-beta-1
  • transforming growth factor beta-1
  • transforming growth factor, beta 1

Background

TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TGF-beta 1
Antibody (1018746) [F
FAB10502F
TGF-beta 1 Antibody (1018746) [FITC]
Species: Hu
Applications: CyTOF-ready, Flow

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Secondary Antibodies

 

Isotype Controls

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Blogs on TGF-beta 1.

Check out the latest blog posts on TGF-beta 1.
TGF-beta 1 - a versatile signaling molecule with roles in development and disease
The transforming growth factor-beta (TGF-beta) family consists of a wide variety of signaling proteins with roles in development. TGF-beta signaling controls growth, differentiation, and immune responses and is often misregulated in cancer. TGF-beta ...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

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