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TfR (Transferrin R) Antibody (TFRC/1817) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, CyTOF-ready
Clone
TFRC/1817
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

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View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-54467AF350
Alexa Fluor 405
NBP2-54467AF405
Alexa Fluor 488
NBP2-54467AF488
Alexa Fluor 532
NBP2-54467AF532
Alexa Fluor 594
NBP2-54467AF594
Alexa Fluor 647
NBP2-54467AF647
Alexa Fluor 700
NBP2-54467AF700
Alexa Fluor 750
NBP2-54467AF750
Biotin
NBP2-54467B
DyLight 350
NBP2-54467UV
DyLight 405
NBP2-54467V
DyLight 488
NBP2-54467G
DyLight 550
NBP2-54467R
DyLight 650
NBP2-54467C
DyLight 680
NBP2-54467FR
DyLight 755
NBP2-54467IR
FITC
NBP2-54467F
HRP
NBP2-54467H
Janelia Fluor 549
NBP2-54467JF549
Janelia Fluor 646
NBP2-54467JF646
Unconjugated
NBP2-54467-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-54467-100ug
Azide and BSA Free
NBP2-54467-100ug
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TfR (Transferrin R) Antibody (TFRC/1817) [DyLight 594] Summary

Immunogen
Recombinant extracellular fragment (around aa 94-212) of human TfR (Transferrin R) protein (exact sequence is proprietary) (Uniprot: P02786)
Localization
Cell surface
Specificity
It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This monoclonal antibody is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TFRC
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TfR (Transferrin R) Antibody (TFRC/1817) [DyLight 594]

  • CD71 antigen
  • CD71
  • CD71TRFR
  • p90
  • T9
  • TfR (Transferrin R)
  • TfR (TransferrinR)
  • TfR
  • TFR1
  • TFRC
  • TR
  • transferrin receptor (p90, CD71)
  • transferrin receptor protein 1
  • TRFR

Background

Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TFRC