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Human Tankyrase 1 ELISA Kit (Chemiluminescence)

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ELISA: Human Tankyrase 1 ELISA Kit (Chemiluminescence) [NBP2-75360] - Samples were spiked with high concentrations of Human Tankyrase 1 and diluted with Reference Standard & Sample Diluent to produce samples with values ...read more
ELISA: Human Tankyrase 1 ELISA Kit (Chemiluminescence) [NBP2-75360] - Standard Curve Reference

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, plasma and other biological fluids
Standard Curve Range
62.50-4000 pg/mL
Sensitivity
37.50 pg/mL

Order Details

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Human Tankyrase 1 ELISA Kit (Chemiluminescence) Summary

Specificity
This kit recognizes Human TNKS1 in samples. No significant cross-reactivity or interference between Human TNKS1 and analogues was observed.
Standard Curve Range
62.50-4000 pg/mL
Sensitivity
37.50 pg/mL
Assay Type
Sandwich-CLIA
Inter-Assay
CV% < 10%
Intra-Assay
CV% < 9.36%
Spike Recovery
87-113%
Sample Volume
100 uL
Kit Type
ELISA Kit (Chemiluminescence)
Gene
TNKS

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Biotinylated Detection Ab Diluent
  2. Concentrated Biotinylated Detection Ab (100x)
  3. Concentrated HRP Conjugate (100x)
  4. Concentrated Wash Buffer (25x)
  5. HRP Conjugate Diluent
  6. Micro CLIA Plate (Dismountable)
  7. Plate Sealer
  8. Product Manual
  9. Reference Standard
  10. Sample Diluent
  11. Substrate Reagent A
  12. Substrate Reagent B

Alternate Names for Human Tankyrase 1 ELISA Kit (Chemiluminescence)

  • EC 2.4.2.30
  • PARP5A
  • PARP-5a
  • PARP5APARPL
  • PARPL
  • pART5
  • Poly [ADP-ribose] polymerase 5A
  • TANK1
  • Tankyrase 1
  • Tankyrase I
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
  • tankyrase-1
  • TIN1TANK1
  • TINF1
  • TINF1TNKS-1
  • TNKS
  • TNKS1TRF1-interacting ankyrin-related ADP-ribose polymerase

Background

The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol TNKS