Human Syndecan-1/CD138 ELISA Kit (Colorimetric)

This product is produced by and distributed for Abnova, a company based in Taiwan.

CD138, also known as Syndecan-1, is a transmembrane heparin sulfate proteoglycan that binds type I collagen. The relative molecular mass of CD138 is found to vary between 20-95 kDa due to the presence of a variable number of GAG modifications on each CD138 molecule. This protein appears to mediate binding of cells to the extracellular matrix. Among mature tissues, CD138 is expressed on simple and stratified epithelia, endothelial cells, and fibroblasts. (2,3) While stratified keratinocytes express CD138, their malignant transformation suppresses CD138 expression. Wound repair processes alter patterns of CD138 expression. Among hematopoietic cells, CD138 is expressed by immunoglobulin-negative pre-B cells in the bone marrow, immature B cells and by terminally differentiated plasma cells in lymphoid organs. CD138 expression has not been observed on mature, circulating peripheral B lymphocytes, however. (4-7) CD138 is also strongly expressed by multiple myeloma-derived cell lines and elevated levels of CD138 are present in the serum of patients with multiple myeloma, a negative prognostic indicator for the disease. (8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using KA3851	Applications	Species
Hye K, Bora L, Byung L et al. The Effect of Tranexamic Acid Administration on Early Endothelial Damage Following Posterior Lumbar Fusion Surgery. J Clin Med. 2021-04-01 [PMID: 33915859]
Na K, Ki K, Ki-Young L et al. Effect of volatile and total intravenous anesthesia on syndecan-1 shedding after minimally invasive gastrectomy: a randomized trial. Sci Rep. 2021-01-15 [PMID: 33452350]
Webster LM, Gill C, Seed PT et al. Chronic hypertension in pregnancy: the impact of ethnicity and superimposed preeclampsia on placental, endothelial and renal biomarkers. Am J Physiol Regul Integr Comp Physiol 2018-03-07 [PMID: 29513563]

Array KA3851

• Syndecan-1/CD138 Antibodies
• Syndecan-1/CD138 ELISA Kits
• Syndecan-1/CD138 Lysate
• Syndecan-1/CD138 Proteins
• Syndecan-1/CD138 ELISA
• Syndecan-1/CD138 Proteins and Enzymes