SRRM1 Antibody

Images

 
Western Blot: SRRM1 Antibody [NBP2-85821] - WB Suggested Anti-Srrm1 Antibody. Titration: 1.0 ug/ml. Positive Control: Rat Brain
Immunohistochemistry-Paraffin: SRRM1 Antibody [NBP2-85821] - Rabbit Anti-Srrm1 antibody. Formalin Fixed Paraffin Embedded Tissue: Human Colon. Primary antibody Concentration: 1:100. Secondary Antibody: Donkey ...read more

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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SRRM1 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of SRRM1. Peptide sequence: PSPVQSQSPSTNWSPAAPAKKAKSPTPSPSPARNSDQEGGGKKKKKKKDK The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
SRRM1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for SRRM1 Antibody

  • MGC39488
  • POP101
  • Ser/Arg-related nuclear matrix protein
  • serine/arginine repetitive matrix 1
  • serine/arginine repetitive matrix protein 1
  • SRm160
  • SRM160160-KD
  • SR-related nuclear matrix protein of 160 kDa

Background

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol SRRM1