SRPX Antibody - BSA Free

SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.

Showing Publication 1 - 1 of 1.

Publication using NBP1-77086	Applications	Species
Ampudia-Mesias E, El-Hadad S, Cameron CS et al. SRPX Emerges as a Potential Tumor Marker in the Extracellular Vesicles of Glioblastoma Cancers 2022-04-14 [PMID: 35454889] (IF/IHC, Human)	IF/IHC	Human

Array NBP1-77086

• SRPX Antibodies
• SRPX Lysate
• SRPX Protein