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SRPX Antibody - BSA Free

Images

 
Western Blot: SRPX Antibody [NBP1-77086] - SK-N-SH cell lysate with SRPX antibody at 0.25 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: SRPX Antibody [NBP1-77086] - Immunofluorescence of SRPX1 in human brain tissue with SRPX1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: SRPX Antibody [NBP1-77086] - Human brain tissue with SRPX antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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SRPX Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1. The immunogen is located within amino acids 30 - 80 of SRPX1. Amino Acid Squence: VGYSHPRYKDTPW
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SRPX
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 5 ug/mL
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 0.25 ug/ml
Control Peptide
SRPX Peptide (NBP1-77086PEP)
Publications
Read Publication using
NBP1-77086 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for SRPX Antibody - BSA Free

  • DRS
  • ETX1SRPX1
  • sushi repeat-containing protein SRPX
  • sushi-repeat containing protein, X-linked
  • sushi-repeat-containing protein, X chromosome
  • sushi-repeat-containing protein, X-linked

Background

SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SRPX Antibody (NBP1-77086)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.


Filter By Application
IF/IHC
(1)
All Applications
Filter By Species
Human
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SRPX Antibody (NBP1-77086) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SRPX
Uniprot