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SP-B/Surfactant Protein B Antibody (RM370)

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Western Blot: SP-B/Surfactant Protein B Antibody (RM370) [NBP2-77431] - Western Blot of human lung tissue lysate using NBP2-77431.
Western Blot: SP-B/Surfactant Protein B Antibody (RM370) [NBP2-77431] - Western Blot of human lung tissue lysate using NBP2-77431.
Immunohistochemistry: SP-B/Surfactant Protein B Antibody (RM370) [NBP2-77431] - Immunohistochemical staining of formalin fixed and paraffin embedded human lung cancer tissue section using NBP2-77431.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
RM370
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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SP-B/Surfactant Protein B Antibody (RM370) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
A peptide corresponding to residues near C-terminus of human SP-B/Surfactant Protein B
Specificity
This antibody reacts to human SP-B/Surfactant Protein B and proSP-B
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
SFTPB
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500-1:1000
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol/PBS, 1% BSA
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for SP-B/Surfactant Protein B Antibody (RM370)

  • 18 kDa pulmonary-surfactant protein
  • 6 kDa protein
  • PSP-B
  • pulmonary surfactant-associated protein B
  • Pulmonary surfactant-associated proteolipid SPL(Phe)
  • SFTB3
  • SFTP3
  • SFTPB
  • SMDP1
  • SP-B surfactant, pulmonary-associated protein B
  • SP-B
  • surfactant protein B

Background

The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SFTPB