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SOS1 Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

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SOS1 Antibody [Janelia Fluor® 525] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1025 and 1075 of human son of sevenless ortholog 1 using the numbering given in entry NP_005624.2 (GeneID 6654).
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SOS1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SOS1 Antibody [Janelia Fluor® 525]

  • GF1GGF1
  • GINGF
  • guanine nucleotide exchange factor
  • HGFhereditary, 1
  • NS4
  • son of sevenless homolog 1 (Drosophila)
  • son of sevenless homolog 1
  • SOS1
  • SOS-1

Background

SOS1 encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional SOS1 Products

Array NBP1-05954JF525

Research Areas for SOS1 Antibody (NBP1-05954JF525)

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Bioinformatics

Gene Symbol SOS1