Species: Hu, Mu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA, Func
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Description
SOS1 encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
6654 |
| Alternate Names |
- GF1GGF1
- GINGF
- guanine nucleotide exchange factor
- HGFhereditary, 1
- NS4
- son of sevenless homolog 1 (Drosophila)
- son of sevenless homolog 1
- SOS-1
|
Research Areas for SOS1
Find related products by research area and learn more about each of the different research areas below.
Breast CancerCancer
