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SOS1 Antibody (SOS-01) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
Clone
SOS-01
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

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SOS1 Antibody (SOS-01) [Janelia Fluor® 585] Summary

Immunogen
Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein (NM_005633.3)
Specificity
The SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SOS1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SOS1 Antibody (SOS-01) [Janelia Fluor® 585]

  • GF1GGF1
  • GINGF
  • guanine nucleotide exchange factor
  • HGFhereditary, 1
  • NS4
  • son of sevenless homolog 1 (Drosophila)
  • son of sevenless homolog 1
  • SOS1
  • SOS-1

Background

SOS1 encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SOS1 Antibody (NB110-68800JF585) (0)

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Secondary Antibodies

 

Isotype Controls

Additional SOS1 Products

Array NB110-68800JF585

Research Areas for SOS1 Antibody (NB110-68800JF585)

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Blogs on SOS1

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Bioinformatics

Gene Symbol SOS1