SOD1/Cu-Zn SOD Antibody

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 5 of 5.

Publications using NB100-60944	Applications	Species
Tracy EP, Dukes M, Beare J et al. Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease Antioxidants & redox signaling 2022-08-11 [PMID: 35950616]
Morton NM, Beltram J, Carter RN et al. Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nat. Med. 2016-06-06 [PMID: 27270587]
Cowley PM, Keslacy S, Middleton FA et al. Functional and biochemical characterization of soleus muscle in Down syndrome mice: insight into the muscle dysfunction seen in the human condition Am J Physiol Regul Integr Comp Physiol 2012-12-01 [PMID: 23115123] (WB, Mouse)	WB	Mouse
DeRuisseau LR, Recca DM, Mogle JA et al. Metallothionein deficiency leads to soleus muscle contractile dysfunction following acute spinal cord injury in mice. Am J Physiol Regulatory Integrative Comp Physiol :00263. 2009-12-01 [PMID: 19828842]
Ghadge GD, Wang L, Sharma K et al. Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord. Neurobiol Dis 2006-01-01 [PMID: 16084730]

Array NB100-60944

• SOD1/Cu-Zn SOD Antibodies
• SOD1/Cu-Zn SOD Antibody Pair
• SOD1/Cu-Zn SOD ELISA Kits
• SOD1/Cu-Zn SOD Lysate
• SOD1/Cu-Zn SOD Proteins