SLC7A5/LAT1 Antibody

Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 3 of 3.

Publications using NBP3-09988	Applications	Species
Rivera CN, Hinkle JS, Watne RM et al. PPAR?/? Agonism with GW501516 Increases Myotube PGC-1? Content and Reduces BCAA Media Content Independent of Changes in BCAA Catabolic Enzyme Expression PPAR research 2023-06-06 [PMID: 37325367] (Western Blot, Mouse)	Western Blot	Mouse
Rivera CN, Watne RM, Brown ZA et al. Effect of AMPK activation and glucose availability on myotube LAT1 expression and BCAA utilization Amino acids 2022-12-22 [PMID: 36547760]
Rivera CN, Watne RM, Brown ZA et al. Effect of AMPK activation and glucose availability on myotube LAT1 expression and BCAA utilization Amino acids 2022-12-22 [PMID: 36547760]

Array NBP3-09988

• SLC7A5/LAT1 Antibodies
• SLC7A5/LAT1 ELISA Kits
• SLC7A5/LAT1 Protein