Species: Hu
Applications: Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Description
Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
8140 |
| Alternate Names |
- 4F2 LC
- CD98
- CD98LC
- D16S469EL-type amino acid transporter 1
- E16
- Integral membrane protein E16
- large neutral amino acids transporter 1
- large neutral amino acids transporter small subunit 1
- LAT1hLAT1
- MPE16CD98 light chain
- sodium-independent neutral amino acid transporter LAT1,4F2LC
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain
- Solute carrier family 7 member 5
- y+ system cationic amino acid transporter
|
Research Areas for SLC7A5/LAT1
Find related products by research area and learn more about each of the different research areas below.
Cancer
