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SLC7A5/LAT1 Antibody (BU53) [PE/Cy5.5]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
BU53
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-50465AF350
Alexa Fluor 405
NBP2-50465AF405
Alexa Fluor 488
NBP2-50465AF488
Alexa Fluor 532
NBP2-50465AF532
Alexa Fluor 594
NBP2-50465AF594
Alexa Fluor 647
NBP2-50465AF647
Alexa Fluor 700
NBP2-50465AF700
Alexa Fluor 750
NBP2-50465AF750
Allophycocyanin
NBP2-50465APC
Allophycocyanin/Cy7
NBP2-50465APCCY7
CoraFluor 1
NBP2-50465CL1
DyLight 350
NBP2-50465UV
DyLight 405
NBP2-50465V
DyLight 488
NBP2-50465G
DyLight 550
NBP2-50465R
DyLight 594
NBP2-50465DL594
DyLight 650
NBP2-50465C
DyLight 680
NBP2-50465FR
DyLight 755
NBP2-50465IR
FITC
NBP2-50465F
Janelia Fluor 525
NBP2-50465JF525
Janelia Fluor 549
NBP2-50465JF549
Janelia Fluor 585
NBP2-50465JF585
Janelia Fluor 635
NBP2-50465JF635
Janelia Fluor 646
NBP2-50465JF646
Janelia Fluor 669
NBP2-50465JF669
PE
NBP2-50465PE
PE/Atto594
NBP2-50465PEATT594
PE/Cy7
NBP2-50465PECY7
PerCP
NBP2-50465PCP
Unconjugated
NBP2-50465
mFluor Violet 450 SE
NBP2-50465MFV450
mFluor Violet 500 SE
NBP2-50465MFV500
mFluor Violet 610 SE
NBP2-50465MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-50465
BSA Free
NBP2-50465
BSA Free
NBP2-50465SS
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SLC7A5/LAT1 Antibody (BU53) [PE/Cy5.5] Summary

Immunogen
Plasma cell line 8226
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SLC7A5
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Cell Surface)
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for SLC7A5/LAT1 Antibody (BU53) [PE/Cy5.5]

  • 4F2 LC
  • 4F2LC
  • CD98
  • CD98lc
  • D16S469EL-type amino acid transporter 1
  • E16
  • Integral membrane protein E16
  • large neutral amino acids transporter 1
  • large neutral amino acids transporter small subunit 1
  • LAT1
  • LAT1hLAT1
  • MPE16
  • MPE16CD98 light chain
  • SLC7A5
  • sodium-independent neutral amino acid transporter LAT1,4F2LC
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain
  • Solute carrier family 7 member 5
  • TA1
  • y+ system cationic amino acid transporter

Background

Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC7A5