SLAM/CD150 Antibody (542301) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Signaling lymphocytic activation molecule (SLAM, SLAMF1; CD150) was the first identified of a family of type I transmembrane (TM) lymphocyte activating receptors. SLAM homotypic adhesion bidirectionally stimulates T and B cells. SLAM is also expressed by hematopoietic stem cells, dendritic cells and platelets and is a T cell measles virus receptor. The 70 kDa glycoprotein contains a 216 amino acid (aa) extracellular domain (ECD) with one C2 type and one V type Ig-like domain, a 20 aa TM sequence and a 76 aa SH2-binding cytoplasmic domain. One splice variant has a shorter cytoplasmic tail and another lacks the TM sequence and is secreted. Human and mouse SLAM ECD share 60% aa identity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Co-Immunoprecipitation, Immunoprecipitation.

Showing Publications 1 - 2 of 2.

Publications using MAB1642	Applications	Species
L von Wenser, C Schulthei beta , S Bolz, S Schliffke, D Simnica, E Willscher, H Gerull, G Wolters-Ei, K Riecken, B Fehse, M Altfeld, P Nollau, M Binder SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2 Leukemia, 2020-08-21;0(0):. 2020-08-21 [PMID: 32826957] (Co-Immunoprecipitation, Immunoprecipitation, Human)	Co-Immunoprecipitation, Immunoprecipitation	Human
Shinji Miyata, Hiroshi Kitagawa Chondroitin 6-Sulfation Regulates Perineuronal Net Formation by Controlling the Stability of Aggrecan Neural Plasticity 1/14/2016 [PMID: 27057358]

Array MAB1642

• SLAM/CD150 Antibodies
• SLAM/CD150 Antibody Pair
• SLAM/CD150 Proteins
• SLAM/CD150 ELISA
• SLAM/CD150 Proteins and Enzymes