Human peripheral blood lymphocytes were stained with Mouse Anti-Human SLAM/CD150 PE-conjugated Monoclonal Antibody (Catalog # FAB1642P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). ...read more
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for SLAM/CD150 Antibody (542301) [Phycoerythrin]
CD 150
CD150
CD150IPO-3
CDw150
IPO-3
signaling lymphocytic activation molecule family member 1
signaling lymphocytic activation molecule
SLAM
SLAMCD150 antigen
SLAMF1
Background
Signaling Lymphocytic Activation Molecule (SLAM), also known as SLAMF1 and CD150, was the first identified family member of type I transmembrane (TM) lymphocyte activating receptors. SLAM homotypic adhesion bidirectionally stimulates T and B cells. SLAM is also expressed by hematopoietic stem cells, dendritic cells and platelets and is a T cell measles virus receptor. The 70 kDa glycoprotein contains a 216 amino acid (aa) extracellular domain (ECD) with one C2 type and one V type Ig-like domain, a 20 aa TM sequence and a 76 aa SH2-binding cytoplasmic domain. One splice variant has a shorter cytoplasmic tail and another lacks the TM sequence and is secreted. Human and mouse SLAM ECD share 60% aa identity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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