SHANK1 Antibody [mFluor Violet 610 SE] Summary
Immunogen |
A synthetic peptide made to an N terminal portion of human SHANK1 protein (between residues 110-160) [UniProt Q9Y566] |
Localization |
Cytoplasmic, Cell junction, Postsynaptic density of neuronal cells. |
Marker |
TGN Marker |
Specificity |
Reacts with residues [ERLLREYPQSFEKGV] of the N terminus of the rat Shank1a protein. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
SHANK1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Reacts with human and rat Shank1a. Does not react with mouse Shank1a.
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for SHANK1 Antibody [mFluor Violet 610 SE]
Background
Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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