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SHANK1 Antibody (M369)

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Western Blot: SHANK1 Antibody (M369) [NBP3-23391] - Western blot of mouse brain lysate. The blot was probed with mouse monoclonal anti-SHANK1 (C-terminal region) antibody at 1:250 (lane 1), 1:500 (lane 2), or 1:1000 ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
M369
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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SHANK1 Antibody (M369) Summary

Description
Stable for at least 1 year at -20°C.
Immunogen
Clone M369 was generated from a sequence corresponding to amino acids in the C-terminal region of rat SHANK1. This sequence has high homology to human and mouse SHANK1. [UniProt# Q9WV48]
Specificity
This antibody detects a 225 kDa protein corresponding to the molecular mass of Shank1 on SDS-PAGE immunoblots of adult mouse brain.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SHANK1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Theoretical MW
225 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C.
Buffer
PBS, 1 mg/ml BSA and 50% glycerol
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for SHANK1 Antibody (M369)

  • SH3 and multiple ankyrin repeat domains 1
  • SH3 and multiple ankyrin repeat domains protein 1
  • Shank1
  • Somatostatin receptor-interacting protein
  • SSTR-interacting protein
  • SSTRIPSPANK-1
  • synamon

Background

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SHANK1