SH3MD2 Antibody (3H3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00057630-M01	Applications	Species
Ying Z, Sandoval M, Beronja S. et al. Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth. Nat Cell Biol 2018-10-22 [PMID: 30361695]
de Bock CE, Hughes MR, Snyder K et al. Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels. FEBS Lett 2017-02-01 [PMID: 28129444]
Wilhelm M, Kukekov NV, Schmit TL et al. Sh3rf2/POSHER promotes cell survival by RING-mediated proteasomal degradation of the JNK scaffold POSH. J Biol Chem. 2011-11-28 [PMID: 22128169]

Array H00057630-M01

• SH3MD2 Antibodies
• SH3MD2 Lysate
• SH3MD2 Protein