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Recombinant Human SH2D1A His Protein

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SDS-Page: Recombinant Human SH2D1A His Protein [NBP1-50869] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
SDS-Page: Recombinant Human SH2D1A His Protein [NBP1-50869] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

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Recombinant Human SH2D1A His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-128 of Human SH2D1A

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
SH2D1A
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
16.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95%, by SDS-PAGE

Alternate Names for Recombinant Human SH2D1A His Protein

  • DSHP
  • DSHPLYP
  • Duncan disease SH2-protein
  • EBVS
  • FLJ92177
  • IMD5
  • LYP
  • MTCP1
  • SAP/SH2D1A
  • SAPlymphoproliferative syndrome
  • SH2 domain containing 1A
  • SH2 domain-containing protein 1A
  • SH2D1A
  • signaling lymphocyte activation molecule-associated protein
  • Signaling lymphocytic activation molecule-associated protein
  • SLAM associated protein/SH2 domain protein 1A
  • SLAM-associated protein
  • T cell signal transduction molecule SAP
  • T-cell signal transduction molecule SAP
  • XLP
  • XLPD
  • XLPDFLJ18687
  • XLPSH2 domain protein 1A

Background

SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Recombinant Human
SH2D1A His Protein
NBP1-50869
Recombinant Human SH2D1A His Protein
Species: Hu
Applications: PAGE

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Bioinformatics

Gene Symbol SH2D1A