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SDNSF/MCFD2 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
AF2357
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF2357
Carrier Free
AF2357
Carrier Free
AF2357-SP
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SDNSF/MCFD2 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human SDNSF/MCFD2
Glu27-Gln146
Accession # Q8NI22
Specificity
Detects human SDNSF/MCFD2 in Western blots. In Western blots, approximately 20% cross‑reactivity with recombinant mouse SDNSF is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MCFD2
Purity Statement
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Readout System

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SDNSF/MCFD2 Antibody [Biotin]

  • DKFZp686G21263
  • F5F8D2
  • LMAN1IP
  • MCFD2
  • multiple coagulation factor deficiency 2
  • multiple coagulation factor deficiency protein 2
  • neural stem cell derived neuronal survival protein
  • Neural stem cell-derived neuronal survival protein
  • SDNSF
  • SDNSFF5F8D

Background

SDNSF, also known as MCFD2 (multiple coagulation factor deficiency 2), was described as a secreted molecule from adult hippocampal neural stem/progenitor cells (ANSC) that functions as an autocrine/paracrine factor to maintain neurogenesis in the central nervous system. It is also a component of the MCDF2-LMAN1 complex that functions as a specific cargo receptor for the ER to golgi transport of proteins. Mutations in MCFD2 causes factor 5 and factor 8 combined deficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MCFD2
Uniprot