LMAN1 Antibody (OTI1A8)

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq].

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Monkey.

We have publications tested in 3 applications: FLOW, ICC/IF, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP2-03381	Applications	Species
Caielli S, Balasubramanian P, Rodriguez-Alcazar J et al. An unconventional mechanism of IL-1? secretion that requires Type I IFN in lupus monocytes bioRxiv : the preprint server for biology 2023-08-03 [PMID: 37577613]
Miller MH, Swaby LG, Vailoces VS et al. LMAN1 is a receptor for house dust mite allergens Cell reports 2023-03-03 [PMID: 36870056] (FLOW, Mouse)	FLOW	Mouse
Cabukusta B, Nettebrock NT, Kol M et al. Ceramide phosphoethanolamine synthase SMSr is a target of caspase-6 during apoptotic cell death Biosci. Rep. 2017-08-31 [PMID: 28659495] (WB, Human)	WB	Human
Gerondopoulos A, Bastos RN, Yoshimura S et al. Rab18 and a Rab18 GEF complex are required for normal ER structure. J. Cell Biol. 2014-06-09 [PMID: 24891604] (ICC/IF, Monkey) Details: COS7 cells expressing GFP-Rab18 immunostained for Rab3GAP1 and markers for COP I (beta-COP), COP II (Sec31), ERGIC-53, and LAMP1 (Figure 3d )	ICC/IF	Monkey

Array NBP2-03381

• LMAN1 Antibodies
• LMAN1 Lysate
• LMAN1 Protein