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IHC |
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Immunohistochemistry |
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IHC |
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IHC-P |
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Greco S, Sanz JM, Bortolotti D et al. Case report: Tissue positivity for SARS-CoV-2 in a preterm born infant death of thrombosis: possible intrauterine transmission Frontiers in medicine 2023-05-11 [PMID: 37250636] (IHC)
Details:
Dilution: 1:250 |
IHC |
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| Vu MN, Morris DR, Alvarado RE et al. Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection bioRxiv : the preprint server for biology 2023-04-18 [PMID: 37131784] (Western Blot) |
Western Blot |
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ELISA |
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Charvet B, Brunel J, Pierquin J et al. SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients iScience 2023-05-19 [PMID: 37091988] (IHC-P)
Details:
1:50 IHC-P dilution |
IHC-P |
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| Jacob IB, Gemmiti A, Xiong W et al. Human Surfactant Protein A Alleviates SARS-CoV-2 Infectivity in Human Lung Epithelial Cells bioRxiv : the preprint server for biology 2023-04-03 [PMID: 37066146] |
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Western Blot |
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ICC/IF |
SARS-CoV-2 |
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IHC-P |
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WB |
Human |
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IHC-P |
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IHC |
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IHC |
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IHC-P |
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IHC-P |
SARS-CoV-2 |
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IHC-P |
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Immunohistochemistry |
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IF/IHC |
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| Finlay JB, Brann DH, Abi Hachem R et al. Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium Science translational medicine 2022-12-21 [PMID: 36542694] (IHC-Fr) |
IHC-Fr |
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| Anderson CF, Wang Q, Stern D et al. Supramolecular filaments for concurrent ACE2 docking and enzymatic activity silencing enable coronavirus capture and infection prevention Matter 2022-12-12 [PMID: 36531610] (WB, IHC-P) |
WB, IHC-P |
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Immunohistochemistry |
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| Kim SH, Kim J, Jang JY et al. Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits Frontiers in Immunology 2022-11-15 [PMID: 36457995] (IF/IHC) |
IF/IHC |
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| Rivera JA, Corchuelo S, Parra EA et al. Inmunohistochemical detection of pandemic SARSCoV- 2 antigens in lung tissue Biomedica : revista del Instituto Nacional de Salud 2022-10-31 [PMID: 36322553] (IHC-P) |
IHC-P |
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ICC/IF |
SARS-CoV-2 |
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IHC-P |
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| Goh D, Lim JCT, Ferna�ndez SB et al. Case report: Persistence of residual antigen and RNA of the SARS-CoV-2 virus in tissues of two patients with long COVID Frontiers in Immunology 2022-09-05 [PMID: 36131932] (Immunohistochemistry) |
Immunohistochemistry |
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IHC-P |
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| Liu Y, Zhang X, Liu J et al. A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions Nature Communications 2022-07-27 [PMID: 35896528] (Western Blot) |
Western Blot |
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IF/IHC |
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| Dinnon, KH;Leist, SR;Okuda, K;Dang, H;Fritch, EJ;Gully, KL;De la Cruz, G;Evangelista, MD;Asakura, T;Gilmore, RC;Hawkins, P;Nakano, S;West, A;Schäfer, A;Gralinski, LE;Everman, JL;Sajuthi, SP;Zweigart, MR;Dong, S;McBride, J;Cooley, MR;Hines, JB;Love, MK;Groshong, SD;VanSchoiack, A;Phelan, SJ;Liang, Y;Hether, T;Leon, M;Zumwalt, RE;Barton, LM;Duval, EJ;Mukhopadhyay, S;Stroberg, E;Borczuk, A;Thorne, LB;Sakthivel, MK;Lee, YZ;Hagood, JS;Mock, JR;Seibold, MA;O'Neal, WK;Montgomery, SA;Boucher, RC;Baric, RS; SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice Science translational medicine 2022-07-07 [PMID: 35857635] |
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IHC-P |
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| Wang Z, Popowski KD, Zhu D et al. Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine Nature biomedical engineering 2022-07-01 [PMID: 35788687] (IHC-P, Hamster) |
IHC-P |
Hamster |
| Escalera A, GarcIa-Sastre A, Aydillo T Protocol to isolate and assess spike protein cleavage in SARS-CoV-2 variants obtained from clinical COVID-19 samples STAR Protocols 2022-09-01 [PMID: 35776647] (WB, SARS-CoV-2) |
WB |
SARS-CoV-2 |
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Western Blot |
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| Kim HK, Kang JA, Lyoo KS et al. Severe acute respiratory syndrome coronavirus 2 and influenza A virus co-infection alters viral tropism and haematological composition in Syrian hamsters Transboundary and emerging diseases 2022-09-01 [PMID: 35648595] (IHC-P) |
IHC-P |
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| Kang YF, Sun C, Sun J et al. Quadrivalent mosaic HexaPro-bearing nanoparticle vaccine protects against infection of SARS-CoV-2 variants Nature communications 2022-05-13 [PMID: 35562337] (IHC-P, SARS-CoV-2) |
IHC-P |
SARS-CoV-2 |
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| Carossino M, Kenney D, O'Connell AK et al. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression Viruses 2022-03-05 [PMID: 35336942] (IF/IHC, SARS-CoV-2) |
IF/IHC |
SARS-CoV-2 |
| Goh D, Lim J, Fernandez S et al. Persistence of residual SARS-CoV-2 viral antigen and RNA in tissues of patients with long COVID-19 Research Square 4459-01-01 (IF/IHC, SARS-CoV-2) |
IF/IHC |
SARS-CoV-2 |
| Chen M, Pekosz A, Villano JS et al. Evolution of nasal and olfactory infection characteristics of SARS-CoV-2 variants bioRxiv : the preprint server for biology 2022-04-12 [PMID: 35441175] (IF/IHC) |
IF/IHC |
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| Maung NC, Liew ZHS, Leow WQ et al. Severe de novo liver injury after Moderna vaccination - not always autoimmune hepatitis Journal of hepatology 2022-04-16 [PMID: 35439566] (IF/IHC) |
IF/IHC |
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| DJ Kenney, AK O'Connell, J Turcinovic, P Montanaro, RM Hekman, T Tamura, AR Berneshawi, TR Cafiero, S Al Abdulla, B Blum, SI Goldstein, BL Heller, HP Gertje, E Bullitt, AJ Trachtenbe, E Chavez, ET Nono, C Morrison, AE Tseng, A Sheikh, S Kurnick, K Grosz, M Bosmann, M Ericsson, BR Huber, M Saeed, AB Balazs, KP Francis, A Klose, N Paragas, JD Campbell, JH Connor, A Emili, NA Crossland, A Ploss, F Douam Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection Cell Reports, 2022-04-04;39(3):110714. 2022-04-04 [PMID: 35421379] |
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| Hartard C, Chaqroun A, Settembre N et al. Multiorgan and Vascular Tropism of SARS-CoV-2 Viruses 2022-03-03 [PMID: 35336922] (IF/IHC) |
IF/IHC |
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| Jarrah SA, Kmetiuk LB, de Carvalho OV et al. Persistent SARS-CoV-2 antigen presence in multiple organs of a naturally infected cat from Brazil The journal of venomous animals and toxins including tropical diseases 2022-03-07 [PMID: 35310131] (IF/IHC) |
IF/IHC |
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| Madden, PJ;Thomas, Y;Blair, RV;Samer, S;Doyle, M;Midkiff, CC;Doyle-Meyers, LA;Becker, ME;Arif, MS;McRaven, MD;Simons, LM;Carias, AM;Martinelli, E;Lorenzo-Redondo, R;Hultquist, JF;Villinger, FJ;Veazey, RS;Hope, TJ; An immunoPET probe to SARS-CoV-2 reveals early infection of the male genital tract in rhesus macaques bioRxiv : the preprint server for biology [PMID: 35262081] (ICC/IF) |
ICC/IF |
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| Rutigliani M, Bozzo M, Barberis A et al. Case Report: A Peculiar Case of Inflammatory Colitis After SARS-CoV-2 Infection Frontiers in immunology 2022-02-09 [PMID: 35222440] (IF/IHC) |
IF/IHC |
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| Rabbani MY, Rappaport J, Gupta MK Activation of Immune System May Cause Pathophysiological Changes in the Myocardium of SARS-CoV-2 Infected Monkey Model Cells 2022-02-10 [PMID: 35203260] (IF/IHC, SARS-CoV-2) |
IF/IHC |
SARS-CoV-2 |
| Liu Y, Zhang X, Liu J et al. A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions bioRxiv : the preprint server for biology 2022-02-15 [PMID: 35194609] (WB, SARS-CoV-2) |
WB |
SARS-CoV-2 |
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SARS-CoV-2 |
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In vivo assay |
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| Rotstein DS, Peloquin S, Proia K et al. Investigation of SARS-CoV-2 infection and associated lesions in exotic and companion animals Veterinary pathology 2022-01-18 [PMID: 35038930] (IF/IHC) |
IF/IHC |
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| Gawish R, Starkl P, Pimenov L et al. ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFN gamma-driven immunopathology eLife 2022-01-13 [PMID: 35023830] (IHC-P) |
IHC-P |
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IF/IHC |
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| Ulrich L, Halwe NJ, Taddeo A et al. Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta Nature 2021-12-22 [PMID: 34937050] (IF/IHC) |
IF/IHC |
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| Sureshchandra S, Lewis SA, Doratt BM et al. Single-cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine JCI Insight 2021-12-22 [PMID: 34935643] (ELISA, Enzyme-linked Immunosorbent Spot) |
ELISA, Enzyme-linked Immunosorbent Spot |
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| Furukawa R, Kitabatake M, Ouji-Sageshima N et al. Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model Scientific reports 2021-12-08 [PMID: 34880383] (WB, SDS-Page) |
WB, SDS-Page |
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| Bortolotti D, Simioni C, Neri LM Et al. Relevance of VEGF and CD147 in different SARS-CoV-2 positive digestive tracts characterized by thrombotic damage FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021-12-01 [PMID: 34822202] (IF/IHC) |
IF/IHC |
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| Muruato A, Vu MN, Johnson BA Et al. Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge PLoS biology 2021-11-01 [PMID: 34735434] (IF/IHC) |
IF/IHC |
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ICC/IF |
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Western Blot |
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| Dong W, Mead H, Tian L et al. The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus Journal of virology 2022-01-12 [PMID: 34668775] (IF/IHC, SARS-CoV-2) |
IF/IHC |
SARS-CoV-2 |
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IHC-P |
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IHC-P |
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Immunohistochemistry, Electron Microscopy |
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IHC-P |
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| Lu M, Zhang Y, Dravid P Et al. A methyltransferase-defective VSV-based SARS-CoV-2 vaccine candidate provides complete protection against SARS-CoV-2 infection in hamsters Journal of virology 2021-08-11 [PMID: 34379509] (IF/IHC) |
IF/IHC |
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| Rizzo S, Savastano MC, Bortolotti D et al. COVID-19 Ocular Prophylaxis: The Potential Role of Ozonated-Oils in Liposome Eyedrop Gel Translational Vision Science & Technology 2021-08-05 [PMID: 34351367] (Immunocytochemistry/ Immunofluorescence) |
Immunocytochemistry/ Immunofluorescence |
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| Williams Cg, Jureka As, Silvas Ja Et Al. Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication Cell reports 2021-07-20 [PMID: 34320401] |
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| Amanat F, Strohmeier S, Lee Wh Et Al. Murine Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Neutralize Authentic Wild-Type SARS-CoV-2 as Well as B.1.1.7 and B.1.351 Viruses and Protect In Vivo in a Mouse Model in a Neutralization-Dependent Manner mBio 2021-07-27 [PMID: 34311574] |
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| Zhang ML, Jacobsen F, Pepe-Mooney BJ et al. Clinicopathological findings in patients with COVID-19-associated ischaemic enterocolitis Histopathology 2021-07-22 [PMID: 34292620] |
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| Kondo Y, Larabee JL, Gao L Et al. L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus JCI insight 2021-07-22 [PMID: 34291736] |
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| Kritselis M, Yambayev I, Prilutskiy A Et Al. Distinctive Pseudopalisaded Histiocytic Hyperplasia Characterizes the Transition of Exudative to Proliferative Phase of Diffuse Alveolar Damage in Patients Dying of COVID-19 Human pathology 2021-07-14 [PMID: 34273395] |
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| Mirza Muhammad Fahd Qadir, Manika Bhondeley, Wandy Beatty, Dina D. Gaupp, Lara A. Doyle-Meyers, Tracy Fischer, Ishitri Bandyopadhyay, Robert V. Blair, Rudolf Bohm, Jay Rappaport, Eric Lazartigues, Richard S. Vander Heide, Jay K. Kolls, Xuebin Qin, Franck Mauvais-Jarvis SARS-CoV-2 infection of the pancreas promotes thrombofibrosis and is associated with new-onset diabetes JCI Insight 2021-08-23 [PMID: 34241597] |
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| Li Z, Wang Z, Dinh PC et al. Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19 Nature Nanotechnology 2021-08-01 [PMID: 34140674] |
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| He X, Chandrashekar A, Zahn R et al. Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques Cell 2021-06-01 [PMID: 34133941] (Immunohistochemistry) |
Immunohistochemistry |
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| Dong W, Wang J, Tian L et al. FXa cleaves the SARS-CoV-2 spike protein and blocks cell entry to protect against infection with inferior effects in B.1.1.7 variant bioRxiv : the preprint server for biology 2021-06-08 [PMID: 34127969] (IHC-P) |
IHC-P |
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| Hassler L, Reyes F, Sparks M et al. Evidence For and Against Direct Kidney Infection by SARS-CoV-2 in Patients with COVID-19 Clinical journal of the American Society of Nephrology : CJASN 2021-06-14 [PMID: 34127485] |
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| Suh J, Mukerji SS, Collens SI et al. Skeletal Muscle and Peripheral Nerve Histopathology in COVID-19 Neurology 2021-08-24 [PMID: 34099523] (Immunohistochemistry) |
Immunohistochemistry |
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| Muruato A, Vu MN, Johnson BA et al. Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge bioRxiv 2023-04-04 [PMID: 33972939] (Immunohistochemistry) |
Immunohistochemistry |
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| Solforosi L, Kuipers H, Jongeneelen M et al. Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP The Journal of experimental medicine 2021-07-05 [PMID: 33909009] (IHC-P) |
IHC-P |
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| Or Alfi, Arkadi Yakirevitch, Ori Wald, Ori Wandel, Uzi Izhar, Esther Oiknine-Djian, Yuval Nevo, Sharona Elgavish, Elad Dagan, Ory Madgar, Gilad Feinmesser, Eli Pikarsky, Michal Bronstein, Olesya Vorontsov, Wayne Jonas, John Ives, Joan Walter, Zichria Zakay-Rones, Menachem Oberbaum, Amos Panet, Dana G. Wolf Human Nasal and Lung Tissues Infected Ex Vivo with SARS-CoV-2 Provide Insights into Differential Tissue-Specific and Virus-Specific Innate Immune Responses in the Upper and Lower Respiratory Tract Journal of Virology 2021-07-01 [PMID: 33893170] |
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| Zaeck L, Scheibner D, Sehl J et al. Light Sheet Microscopy-Assisted 3D Analysis of SARS-CoV-2 Infection in the Respiratory Tract of the Ferret Model Viruses 2021-03-23 [PMID: 33807059] (SARS-CoV-2) |
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SARS-CoV-2 |
| Novelli G, Liu J, Biancolella M et al. Inhibition of HECT E3 ligases as potential therapy for COVID-19 Cell death & disease 2021-03-24 [PMID: 33762578] (IHC-P) |
IHC-P |
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| van der Lubbe JEM, Rosendahl Huber SK, Vijayan A et al. Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease NPJ vaccines 2021-03-19 [PMID: 33741993] (IHC-P) |
IHC-P |
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| #N/A Abstracts from USCAP 2021: Infectious Disease Pathology (757-770) Laboratory Investigation 2021-03-01 [PMID: 33707722] |
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| 0 Abstracts from USCAP 2021: Infectious Disease Pathology (757-770). Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2021-03-13 [PMID: 33707672] |
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| Amanat F, Strohmeier S, Rathnasinghe R et al. Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model mBio 2021-03-02 [PMID: 33653892] (IHC-P) |
IHC-P |
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| Muller JA, Grob R, Conzelmann C, et al. SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas Nat Metab 2021-02-04 [PMID: 33536639] (IHC-P) |
IHC-P |
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| He X, Chandrashekar A, Zahn R, et al. Low-Dose Ad26.COV2.S Protection Against SARS-CoV-2 Challenge in Rhesus Macaques bioRxiv 2021-01-27 [PMID: 33532782] (IHC-P) |
IHC-P |
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| Urata S, Maruyama J, Kishimoto-Urata M et al. Regeneration Profiles of Olfactory Epithelium after SARS-CoV-2 Infection in Golden Syrian Hamsters ACS chemical neuroscience 2021-02-17 [PMID: 33522795] (IF/IHC, SARS-CoV-2) |
IF/IHC |
SARS-CoV-2 |
| Shiho Chiba, Peter J. Halfmann, Masato Hatta, Tadashi Maemura, Shufang Fan, Tammy Armbrust, Olivia M. Swartley, LaTasha K. Crawford, Yoshihiro Kawaoka Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection Emerging Infectious Diseases 2021-02-01 [PMID: 33496650] |
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| Gauchotte G, Venard V, Segondy M, et al. SARS-Cov-2 fulminant myocarditis: an autopsy and histopathological case study International journal of legal medicine 2021-01-03 [PMID: 33392658] (IHC-P, SARS-CoV-2) |
IHC-P |
SARS-CoV-2 |
| Sun, W, Leist, S R Et al. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate. bioRxiv 2020-07-28 [PMID: 33232870] (IHC) |
IHC |
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| Bain, W G, PeNaloza, H F Et al. Lower Respiratory Tract Myeloid Cells Harbor SARS-Cov-2 and Display an Inflammatory Phenotype. Chest 2021-03-01 [PMID: 33217417] (IF/IHC) |
IF/IHC |
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| Giovanna S. Manzano, Jared K. Woods, Anthony A. Amato Covid-19–Associated Myopathy Caused by Type I Interferonopathy The New England Journal of Medicine 2020-11-20 [PMID: 33216474] |
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Rathnasinghe R, Strohmeier S, Amanat F et al. Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection Emerg Microbes Infect 2020-12-01 [PMID: 33073694] (IHC-P, Virus)
Details:
Immunohistochemical analysis of lungs and brain tissue of K18 transgenic mice infected with SARS-CoV2 or C57BL/6J mice that had been injected with hACE2-expressing adenovirus. |
IHC-P |
Virus |
| Aid M, Busman-Sahay K, Vidal SJ et al. Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques Cell 2020-10-09 [PMID: 33065030] |
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| Gordon, D E, Hiatt, J Et al. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science 2020-12-04 [PMID: 33060197] (ICC/IF) |
ICC/IF |
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| Leist SR, Dinnon KH, SchAfer A et al. A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice Cell 2020-09-23 [PMID: 33031744] (IHC-P) |
IHC-P |
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| Amanat F, Strohmeier S, Rathnasinghe R et al. Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model bioRxiv : the preprint server for biology 2020-09-17 [PMID: 32995785] (IHC-P, SARS-CoV-2) |
IHC-P |
SARS-CoV-2 |
| Jeremiah SS, Miyakawa K, Morita T et al. Potent antiviral effect of silver nanoparticles on SARS-CoV-2 Biochemical and biophysical research communications 2020-09-11 [PMID: 32958250] (ICC/IF, SARS-CoV-2) |
ICC/IF |
SARS-CoV-2 |
| Tostanoski LH, Wegmann F, Martinot AJ et al. Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters Nat. Med. 2020-09-03 [PMID: 32884153] (IHC-P, SARS-CoV-2) |
IHC-P |
SARS-CoV-2 |
| Johnson BA, Xie X, Kalveram B et al. Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis bioRxiv 2020-08-26 [PMID: 32869021] (WB, Virus) |
WB |
Virus |
| Dinnon K, Leist S, Schater A et al. A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures Nature 2020-08-27 [PMID: 32854108] (IHC-P) |
IHC-P |
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| Schlottau K, Rissmann M, Graaf A et al. SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study The Lancet Microbe 2020-01-01 [PMID: 32838346] (IHC-P) |
IHC-P |
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Desai N, Neyaz A, Szabolcs A et al. Temporal and Spatial Heterogeneity of Host Response to SARS-CoV-2 Pulmonary Infection medRxiv 2020-08-02 [PMID: 32766600]
Details:
Citation using the Azide and BSA Free format of this antibody. |
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| Rapkiewicz A, Mai X, Carsons S et al. Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series EClinicalMedicine 2020-06-01 [PMID: 32766543] (IF/IHC) |
IF/IHC |
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| Hecht J, Quade B, Deshpande V et al. SARS-CoV-2 can infect the placenta and is not associated with specific placental histopathology: a series of 19 placentas from COVID-19-positive mothers. Mod Pathol 2020-08-02 [PMID: 32741970] (ISH, RNAScope, IF/IHC, Virus) |
ISH, RNAScope, IF/IHC |
Virus |
| Solomon I H; Padera R Answer to August 2020 Photo Quiz. J Clin Microbiol 2020-01-23 [PMID: 32703890] (IF/IHC, Virus) |
IF/IHC |
Virus |
| Bryche B, Albin A, Meri S et al. Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters. Brain Behav Immun. 2020-07-03 [PMID: 32629042] (IHC-Fr) |
IHC-Fr |
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| Schaefer IM, Padera RF, Solomon IH et al. In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19 Mod. Pathol. 2020-06-19 [PMID: 32561849] (IHC-P, IF/IHC) |
IHC-P, IF/IHC |
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| Solomon IH, Normandin E, Bhattacharyya S et al. Neuropathological Features of Covid-19 New England Journal of Medicine 2020-09-03 [PMID: 32530583] (Immunohistochemistry, Immunohistochemistry-Paraffin) |
Immunohistochemistry, Immunohistochemistry-Paraffin |
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| Jureka AS, Silvas JA, Basler CF Propagation, inactivation, and safety testing of SARS-CoV-2 bioRxiv 2020-01-01 [PMID: 32517266] (ICC/IF, WB) |
ICC/IF, WB |
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| Dinnon K, Leist S, Schafer A et al. A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures. bioRxiv 2020-07-05 [PMID: 32511406] (IF/IHC) |
IF/IHC |
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| Munster V, Feldmann F, Williamson B et al. Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2 bioRxiv 2020-06-09 [PMID: 32511299] |
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| Martines R, Ritter J, Matkovic E et al. Pathology and Pathogenesis of SARS-CoV-2 Associated With Fatal Coronavirus Disease, United States Emerg Infect Dis. 2020-05-21 [PMID: 32437316] (IF/IHC, SARS-CoV, SARS-CoV-2) |
IF/IHC |
SARS-CoV, SARS-CoV-2 |
Chandrashekar A, Liu J, Martinot A et al. SARS-CoV-2 Infection Protects Against Rechallenge in Rhesus Macaques Science. 2020-05-20 [PMID: 32434946] (IHC-P, IF/IHC, Dual ISH-IHC, SARS-CoV-2)
Details:
SARS-CoV2 anti-sense specific probe v-nCoV2019-S (ACD Cat. No. 848561) targeting the positive-sense viral RNA, SARS-CoV2 sense specific probe vnCoV2019-orf1ab-sense (ACD Cat. No. 859151) targeting the negative-sense genomic viral RNA |
IHC-P, IF/IHC, Dual ISH-IHC |
SARS-CoV-2 |
Munster V, Feldmann F, Williamson B et al. Respiratory Disease in Rhesus Macaques Inoculated With SARS-CoV-2 Nature. 2020-05-12 [PMID: 32396922] (IHC-P, SARS-CoV-2)
Details:
Validation of cross-reactivity of SARS-CoV to SARS-CoV-2 in IHC was done in-house by embedding SARS-CoV-2 infected Vero cells in histogel and producing and staining histology slides. |
IHC-P |
SARS-CoV-2 |
| van Doremalen N, Schafer A, Menachery VD et al. SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (Rousettus aegyptiacus) Viruses 2018-12-19 [PMID: 30572566] (IHC-P, Viral) |
IHC-P |
Viral |
| Channappanavar R, Fett C, Mack M et al. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. J. Immunol. 2017-04-03 [PMID: 28373583] (IF/IHC, Virus) |
IF/IHC |
Virus |
| Fehr AR, Channappanavar R, Jankevicius G et al. The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection. MBio. 2016-12-13 [PMID: 27965448] (WB) |
WB |
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| Channappanavar R, Fehr AR, Vijay R et al. Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice Cell Host Microbe 2016-02-10 [PMID: 26867177] (IHC-P, Virus) |
IHC-P |
Virus |
Narayanan K, Ramirez Si, Lokugamage Kg et al. Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression Virus Res. 2014-11-26 [PMID: 25432065] (WB)
Details:
Sars Spike Protein antibody used for WB on Vero E6 cells which were either mock-infected (Mock) or infected with wt SARS-CoV (WT) or SARS-CoV-mt (mt), carrying the mutations K164A and H165A in nsp1, at an MOI of 5. |
WB |
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| Yasui F, Kohara M, Kitabatake M et al. Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus. Virology 2014-04-01 [PMID: 24725942] (IHC-P) |
IHC-P |
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| Amanat F In Depth Characterization of Immune Response Against the Spike Protein of Sars-CoV-2 in Response to Infection and mRna Vaccination Thesis 1905-07-13 |
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| Grunewald ME Adp-Ribosylation During Coronavirus Infection: Connections to Viral Protein Modification, Innate Immunity, and the Toxin Response Thesis 2021-01-01 (WB) |
WB |
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Bagato O, Balkema-Buschmann A, Todt D et al. Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs bioRxiv 2023-03-22 (Immunohistochemistry-Paraffin)
Details:
1:200 IHC-P dilution |
Immunohistochemistry-Paraffin |
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| Ullah I, Ladinsky M, Sharma L et al. A Protective Role for the Lectin CD169/Siglec-1 During SARS-CoV-2 Infection Available at SSRN 2023-07-21 |
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Da Silva Filho J, Herder V, Gibbins M et al. Disease trajectories in hospitalized COVID-19 patients are predicted by clinical and peripheral blood signatures representing distinct lung pathologies medRxiv 2023-09-09 (IHC-P, MS)
Details:
5 ug/mL dilution IHC-P |
IHC-P, MS |
|
| Castaneda D, Jangra S, Yurieva M et al. Protocol for primary human lung organoid-derived air-liquid interfacein vitromodel to study response to SARS-CoV-2 bioRxiv 2023-09-12 (IHC-Fr, Virus) |
IHC-Fr |
Virus |
| Nagaraj S, Joy C, Narayan R et al. SARS-CoV-2 variants of concern exhibit differential gastro-intestinal tropism and pathogenesis in the Syrian golden hamster model bioRxiv 2023-06-20 (IHC-P) |
IHC-P |
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| Yoshikawa Tomoki, Hill Terence E, Yoshikawa Naoko et al. Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection. PLoS One. 2010-01-01 [PMID: 20090954] (IF/IHC) |
IF/IHC |
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| Watts D M, Peters C J, Newman P et al. Evaluation of cotton rats as a model for severe acute respiratory syndrome. Vector Borne Zoonotic Dis. 2008-06-01 [PMID: 18447621] (IF/IHC) |
IF/IHC |
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| Liniger M, Zuniga A, Tamin A et al. Induction of neutralising antibodies and cellular immune responses against SARS coronavirus by recombinant measles viruses. Vaccine. 2008-04-16 [PMID: 18346823] |
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| Mossel EC, Wang J, Jeffers S et al. SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells. Virology. 2008-03-01 [PMID: 18022664] |
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| Tseng CT, Huang C, Newman P et al. Severe acute respiratory syndrome coronavirus infection of mice transgenic for the human Angiotensin-converting enzyme 2 virus receptor. J Virol. 2007-02-01 [PMID: 17108019] |
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| Spruth Martin, Kistner Otfried, Savidis-Dacho Helga et al. A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralising and protective antibody responses. Vaccine. 2006-01-30 [PMID: 16214268] |
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| Nampoothiri S, Sauve F, Ternier G et al. The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis bioRxiv 2020-06-10 (ICC/IF) |
ICC/IF |
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| van der Lubbe J, Rosendahl Huber S, Vijayan A, et al. Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection after sub-optimal vaccine dosing bioRxiv 2021-01-10 (IHC-P, SARS-CoV-2) |
IHC-P |
SARS-CoV-2 |
| Lyoo K, Yeo Y, Lee S et al. Pathogenicity of SARS-CoV-2 and MERS-CoV in Beagle Dogs Research Square 2021-03-04 (IHC-P) |
IHC-P |
|
| Lokugamage Kumari G, Yoshikawa-Iwata Naoko, Ito Naoto et al. Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV. Vaccine. 2008-02-06 [PMID: 18191004] (WB) |
WB |
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Zhang L, Wei L, Jiang D et al. SARS-CoV nucleocapsid protein induced apoptosis of COS-1 mediated by the mitochondrial pathway. Artif Cells Blood Substit Immobil Biotechnol. 2007-01-01 [PMID: 17453707]
Details:
WB: Fig. 1 (COS-1, Huh-7, and Hep2 transiently or mock-transfected with SARS Matrix, Spike, or Nucleocapsid proteins), Antibodies were transfected validated. Imgenex products cited: 1. SARS-Spike (IMG-5119A) 2. SARS-Spike (IMG-5015) 3. SARS-M (IMG-5125A). |
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Show All 172 Publications.
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![Immunohistochemistry: SARS Nucleocapsid Protein Antibody [NB100-56576] - Immunostaining of severe acute respiratory syndrome coronavirus 2 in pulmonary tissues from fatal coronavirus disease cases. A) P5 (Patient 5): scattered immunostaining of tracheal epithelial cells. B) P5: higher magnification shows immunostaining of ciliated cells. C) P8: immunostaining of desquamated type I pneumocyte in an alveolar lumen. D) P4: colocalization of SARS-CoV-2 viral antigen (red) with type II pneumocyte stained by surfactant (brown; arrow). E) P4: colocalization of SARS-CoV-2 viral antigen (red) with macrophages stained by CD163 (brown; arrows); virus immunostaining within type II pneumocytes is also seen (arrowheads). F) P4: extensive immunostaining of hyaline membranes in a region of exudative DAD. G) P3: scattered immunostaining within macrophage in hilar lymph node; anthracosis is also present. Emerg Infect Dis. 2020 May 21;26(9) 10.3201/eid2609.202095, PMID: 32437316](http://images.novusbio.com/fullsize/SARS-Nucleocapsid-Protein-Antibody-Immunohistochemistry-NB100-56576-img0005.jpg "Immunohistochemistry: SARS Nucleocapsid Protein Antibody [NB100-56576] - Immunostaining of severe acute respiratory syndrome coronavirus 2 in pulmonary tissues from fatal coronavirus disease cases. A) P5 (Patient 5): scattered immunostaining of tracheal epithelial cells. B) P5: higher magnification shows immunostaining of ciliated cells. C) P8: immunostaining of desquamated type I pneumocyte in an alveolar lumen. D) P4: colocalization of SARS-CoV-2 viral antigen (red) with type II pneumocyte stained by surfactant (brown; arrow). E) P4: colocalization of SARS-CoV-2 viral antigen (red) with macrophages stained by CD163 (brown; arrows); virus immunostaining within type II pneumocytes is also seen (arrowheads). F) P4: extensive immunostaining of hyaline membranes in a region of exudative DAD. G) P3: scattered immunostaining within macrophage in hilar lymph node; anthracosis is also present. Emerg Infect Dis. 2020 May 21;26(9) 10.3201/eid2609.202095, PMID: 32437316")
![Immunohistochemistry: SARS Nucleocapsid Protein Antibody [NB100-56576] - Pathological changes in rhesus macaques infected with SARS-CoV-2. (g) SARSCoV-2 antigen is detected by immunohistochemistry in type I pneumocytes. Magnification 400x. (j) SARS-CoV-2 antigen is detected by immunohistochemistry in type I pneumocytes (asterisk) and type II pneumocytes (arrow) as well as alveolar macrophages (arrowheads). Magnification 400x. (k) SARS-CoV-2 antigen is detected by immunohistochemistry in mediastinal lymph node. Magnification 400x. (l) SARSCoV-2 antigen is detected by immunohistochemistry in macrophages and lymphocytes in the lamina propria of the cecum. Magnification 400x. bioRxiv March 21, 2020 //doi.org/10.1101/2020.03.21.001628](http://images.novusbio.com/fullsize/SARS-Nucleocapsid-Protein-Antibody-Immunohistochemistry-NB100-56576-img0004.jpg "Immunohistochemistry: SARS Nucleocapsid Protein Antibody [NB100-56576] - Pathological changes in rhesus macaques infected with SARS-CoV-2. (g) SARSCoV-2 antigen is detected by immunohistochemistry in type I pneumocytes. Magnification 400x. (j) SARS-CoV-2 antigen is detected by immunohistochemistry in type I pneumocytes (asterisk) and type II pneumocytes (arrow) as well as alveolar macrophages (arrowheads). Magnification 400x. (k) SARS-CoV-2 antigen is detected by immunohistochemistry in mediastinal lymph node. Magnification 400x. (l) SARSCoV-2 antigen is detected by immunohistochemistry in macrophages and lymphocytes in the lamina propria of the cecum. Magnification 400x. bioRxiv March 21, 2020 //doi.org/10.1101/2020.03.21.001628")
![Dual RNAscope ISH-IHC: SARS Nucleocapsid Protein Antibody [NB100-56576] - Formalin-fixed paraffin-embedded tissue sections of SARS-CoV-2 infected human lung tissue were probed for SARS-CoV-2 viral RNA (ACD anti-sense specific probe v-nCoV2019-S (848561); Fast Red chromogen, ACD [322360]). Adjacent tissue section was processed for immunohistochemistry using rabbit polyclonal anti-SARS Nucleocapsid Antibody [NB100-56576] at 15ug/mL with 1 hr incubation at 25 degrees Celsius followed by incubation with anti-rabbit IgG VisUCyte HRP Polymer Antibody [VC003] and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to SARS-CoV-2 infected cells.](http://images.novusbio.com/fullsize/SARS-Nucleocapsid-Protein-Antibody-Dual-RNAscope-ISH-IHC-NB100-56576-img0006.jpg "Dual RNAscope ISH-IHC: SARS Nucleocapsid Protein Antibody [NB100-56576] - Formalin-fixed paraffin-embedded tissue sections of SARS-CoV-2 infected human lung tissue were probed for SARS-CoV-2 viral RNA (ACD anti-sense specific probe v-nCoV2019-S (848561); Fast Red chromogen, ACD [322360]). Adjacent tissue section was processed for immunohistochemistry using rabbit polyclonal anti-SARS Nucleocapsid Antibody [NB100-56576] at 15ug/mL with 1 hr incubation at 25 degrees Celsius followed by incubation with anti-rabbit IgG VisUCyte HRP Polymer Antibody [VC003] and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to SARS-CoV-2 infected cells.")
![Immunohistochemistry: SARS Nucleocapsid Protein Antibody [NB100-56576] - Characteristics of 2B4 cells clonally derived from human bronchial epithelial Calu-3 cells. Finally, 2B4 cells (passage 6) were infected with SARS-CoV (MOI = 0.1) for 24, 48, and 72 hrs before being fixed with 4% paraformaldehyde for monitoring the morphological changes of infected cells, as visualized by the expression of SARS-CoV NP protein (red) by using the standard IHC (F). Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0008729) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/SARS-Nucleocapsid-Protein-Antibody-Immunohistochemistry-NB100-56576-img0003.jpg "Immunohistochemistry: SARS Nucleocapsid Protein Antibody [NB100-56576] - Characteristics of 2B4 cells clonally derived from human bronchial epithelial Calu-3 cells. Finally, 2B4 cells (passage 6) were infected with SARS-CoV (MOI = 0.1) for 24, 48, and 72 hrs before being fixed with 4% paraformaldehyde for monitoring the morphological changes of infected cells, as visualized by the expression of SARS-CoV NP protein (red) by using the standard IHC (F). Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0008729) licensed under a CC-BY license.")
![Western Blot: SARS Nucleocapsid Protein Antibody [NB100-56576] - Western blot shows recombinant SARS-CoV-2 Nucleocapsid protein. PVDF membrane was probed with 1 ug/mL of Rabbit Anti-SARS-CoV-2 Nucleocapsid Polyclonal Antibody (Catalog # NB100-56576) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (HAF008). A specific band was detected for SARS-CoV-2 Nucleocapsid at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1](http://images.novusbio.com/fullsize/SARS-Nucleocapsid-Protein-Antibody-Western-Blot-NB100-56576-img0007.jpg "Western Blot: SARS Nucleocapsid Protein Antibody [NB100-56576] - Western blot shows recombinant SARS-CoV-2 Nucleocapsid protein. PVDF membrane was probed with 1 ug/mL of Rabbit Anti-SARS-CoV-2 Nucleocapsid Polyclonal Antibody (Catalog # NB100-56576) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (HAF008). A specific band was detected for SARS-CoV-2 Nucleocapsid at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1")
![Western Blot: SARS Nucleocapsid Protein Antibody [NB100-56576] - analysis of SARS Nucleocapsid in (A) untransfected mouse melanoma cell lysate and (B) transfected cell lysate using this antibody.](http://images.novusbio.com/fullsize/SARS-Nucleocapsid-Protein-Antibody-Western-Blot-NB100-56576-img0002.jpg "Western Blot: SARS Nucleocapsid Protein Antibody [NB100-56576] - analysis of SARS Nucleocapsid in (A) untransfected mouse melanoma cell lysate and (B) transfected cell lysate using this antibody.")
![Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).](https://images.novusbio.com/images/Goat-anti-Rabbit-IgG-H+L-Secondary-Antibody-HRP-Western-Blot-NB7160-img0001.jpg "Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).")
![Flow Cytometry: Rabbit IgG Isotype Control [NBP2-24891] - Intracellular FACS analysis of mouse TLR6 polyclonal antibody (red), rabbit isotype control (green), RAW cells alone (shaded). Two micrograms of antibodies were used. Goat anti-rabbit FITC (Novus, 20302) was used as secondary.](https://images.novusbio.com/images/Rabbit--Mouse-IgG-Isotype-Control-Flow-Cytometry-NBP2-24891-img0001.jpg "Flow Cytometry: Rabbit IgG Isotype Control [NBP2-24891] - Intracellular FACS analysis of mouse TLR6 polyclonal antibody (red), rabbit isotype control (green), RAW cells alone (shaded). Two micrograms of antibodies were used. Goat anti-rabbit FITC (Novus, 20302) was used as secondary.")