ROR2 Antibody (Ozuriftamab) - Humanized Summary
Description |
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.1 kDa.
Also known as 'Ozuriftamab'.
Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles. |
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
ROR2 |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Human |
Gene |
ROR2 |
Purity |
Protein A purified |
Endotoxin Note |
< 0.001EU/ug,determined by LAL method. |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Flow Cytometry
- Functional
|
Packaging, Storage & Formulations
Storage |
Store at 4C. |
Buffer |
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2) |
Preservative |
No Preservative |
Concentration |
LYOPH |
Purity |
Protein A purified |
Reconstitution Instructions |
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex. |
Alternate Names for ROR2 Antibody (Ozuriftamab) - Humanized
Background
ROR2 is encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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