Home » ROR gamma t/RORC2/NR1F3 » ROR gamma t/RORC2/NR1F3 Antibodies » ROR gamma t/RORC2/NR1F3 Antibody (600380) [Phycoerythrin]

ROR gamma t/RORC2/NR1F3 Antibody (600380) [Phycoerythrin]

 (6 Publications)
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CD4+/CD8+mouse thymocytes were stained with Mouse Anti-Human/Mouse ROR gammat/RORC2/NR1F3 PE-conjugated Monoclonal Antibody (Catalog # IC6006P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.
CD4+/CD8+mouse thymocytes were stained with Mouse Anti-Human/Mouse ROR gammat/RORC2/NR1F3 PE-conjugated Monoclonal Antibody (Catalog # IC6006P, filled histogram) or isotype control antibody (Catalog # IC0041P, open ...read more
Human peripheral blood mononuclear cells (PBMCs) treated with PMA, Calcium Ionomycin, LPS, and Recombinant Human IL-23 (Catalog # 1290-IL) were stained with Mouse Anti-Human/Mouse ROR gammat/RORC2/ NR1F3 PE-conjugated ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow
Clone
600380
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Phycoerythrin
IC6006P-025
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
IC6006P-025
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ROR gamma t/RORC2/NR1F3 Antibody (600380) [Phycoerythrin] Summary

Immunogen
Human ROR gamma t peptide
Met1-Arg10
Accession # P51449
Specificity
Detects human and mouse ROR gamma t/RORC2 in direct ELISAs. In direct ELISAs, no cross-reactivity with human and mouse RORC.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
RORC
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
IC6006P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ROR gamma t/RORC2/NR1F3 Antibody (600380) [Phycoerythrin]

  • IMD42;NR1F3;Nuclear receptor ROR-gamma;RORG;RZRG;RZR-GAMMA;TOR
  • ROR gamma t
  • RORC2

Background

Retinoic acid-related Orphan Receptor gamma (ROR gamma , TOR, RORC; NR1F3) is a member of the orphan nuclear receptor family. ROR gamma is expressed in the muscle, thymus, testis, pancreas, prostate, heart, and liver. ROR gamma plays a role in thymocyte development and homeostasis. RORs bind to DNA as monomers on half-site elements with 5' A/T-rich extensions. An N-terminal isoform of ROR gamma , ROR gamma t, has been shown to be specifically expressed in the thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ROR gamma t/RORC2/NR1F3 Antibody (IC6006P)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.


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Flow Cytometry
(3)
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Human
(2)
Mouse
(1)
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Showing Publications 1 - 6 of 6.
Publications using IC6006P Applications Species
Mahmoud Abdelbary, Riyaz Mohamed, Ellen E. Gillis, Karl Diaz-Sanders, Babak Baban, Michael W. Brands et al. Sex differences in apoptosis do not contribute to sex differences in blood pressure or renal T cells in spontaneously hypertensive rats Frontiers in Physiology 10/11/2022 [PMID: 36304583]
AK Schmitt, MA Puppa, I Wessels, L Rink Vitamin D3 and zinc synergistically induce regulatory T cells and suppress interferon-gamma production in mixed lymphocyte culture The Journal of nutritional biochemistry, 2022-01-19;0(0):108942. 2022-01-19 [PMID: 35063658] (Flow Cytometry, Human) Flow Cytometry Human
SC Ray, B Baban, MA Tucker, AJ Seaton, KC Chang, EC Mannon, J Sun, B Patel, K Wilson, JB Musall, H Ocasio, D Irsik, JA Filosa, JC Sullivan, B Marshall, RA Harris, PM O'Connor Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells J. Immunol., 2018-04-16;0(0):. 4/16/2018 [PMID: 29661827]
Jeremy A Sullivan, Ewa Jankowska-Gan, Subramanya Hegde, Matthew A Pestrak, Vrushali V Agashe, Arick C Park et al. Th17 Responses to Collagen Type V, k alpha 1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life American Journal of Transplantation 4/1/2017 [PMID: 27801552]
Kathania M, Khare P, Zeng M, Cantarel B, Zhang H, Ueno H, Venuprasad K Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-gammat ubiquitination. Nat Immunol, 2016-06-20;17(8):997-1004. 2016-06-20 [PMID: 27322655] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature, 2012-04-26;484(7395):514-8. 2012-04-26 [PMID: 22466287] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol RORC
Uniprot