Ropporin 1-like Antibody

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Immunohistochemistry-Paraffin: Ropporin 1-like Antibody [NB100-56418] - IHC analysis of ASP in human pancreatic tumor tissue using this antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Ropporin 1-like Antibody Summary

Immunogen
Amino acids 58-73 (KDRMEMPTATQKTDTG) and 176-191 (ARLDSDVSPLETESYL) of human ASP protein were used as the immunogen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ROPN1L
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:100

Reactivity Notes

Expected from sequence similarity: Bovine, Chimpanzee, canine and mouse

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for Ropporin 1-like Antibody

  • AKAP-associated sperm protein
  • ASPFLJ23003
  • FLJ25776
  • radial spoke head 11 homolog
  • rhophilin associated tail protein 1-like
  • ROPN1-like protein
  • ropporin 1-like
  • ropporin-1-like protein
  • RSPH11

Background

AKAPs act as scaffolding proteins co-ordinating phosphotase/kinase signaling at the cytoskeleton. They interact with PKAs and anchor them to specific sub-cellular compartments and participate in multiple cellular processes including growth, metabolism and differentiation. ASP, a 26KDa protein, is a novel AKAP-interacting protein. It interacts with the amphipathic helix of AKAP3 and facilitates AKAP3-PKA interactions. It consists of a conserved N-terminal AKAP-binding domain and a central cysteine-rich Fz domain. It is specifically expressed in the sperms and might play a significant role in sperm motily and also facilitate cytoskeletal reorganization during spermiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ROPN1L
Entrez
Uniprot