ROBO1 Antibody (10E2-R) Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Recombinant protein within Human ROBO1 aa 51-300 / 1,651. (Uniprot: Q9Y6N7) |
Localization |
Cell membrane, Cell projection, axon, Endoplasmic reticulum-Golgi intermediate compartment membrane. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
ROBO1 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:200-1:600
- Western Blot 1:1000
|
Theoretical MW |
181 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH7.4), 0.1% BSA and 40% Glycerol |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Alternate Names for ROBO1 Antibody (10E2-R)
Background
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. In Drosophila, the roundabout gene, a member of the immunoglobulin gene superfamily, encodes an integral membrane protein that is both an axon guidance receptor and a cell adhesion receptor. This receptor is involved in the decision by axons to cross the central nervous system midline. The protein encoded by this gene is structurally similar to the Drosophila roundabout protein. Two transcript variants encoding different isoforms have been found for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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